Abstract
Two of three nurse sharks, Ginglymostoma cirratum, immunized with streptococcal A-variant vaccine, produced over 7 mg/ml serum of 19S IgM antibody to the group-specific carbohydrate. The light chains of this specific antibody from one shark were separated into multiple bands by disc electrophoresis. The light chains from the other antibody-producing animal were much less heterogeneous and gave only one predominant band.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Clem I. W., De Boutaud F., Sigel M. M. Phylogeny of immunoglobulin structure and function. II. Immunoglobulins of the nurse shark. J Immunol. 1967 Dec;99(6):1226–1235. [PubMed] [Google Scholar]
- Clem L. W., Small P. A., Jr Phylogeny of immunoglobulin structure and function. I. Immunoglobulins of the lemon shark. J Exp Med. 1967 May 1;125(5):893–920. doi: 10.1084/jem.125.5.893. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Clem L. W., Small P. A., Jr Phylogeny of immunoglobulin structure and function. V. Valences and association constants of teleost antibodies to a haptenic determinant. J Exp Med. 1970 Sep 1;132(3):385–400. doi: 10.1084/jem.132.3.385. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Haber E. Antibodies of restricted heterogeneity for structural study. Fed Proc. 1970 Jan-Feb;29(1):66–71. [PubMed] [Google Scholar]
- Hill W. C., Cebra J. J. Horse anti-SI immunoglobulins. I. Properties of gamma-M-antibody. Biochemistry. 1965 Dec;4(12):2575–2584. doi: 10.1021/bi00888a005. [DOI] [PubMed] [Google Scholar]
- KRAUSE R. M., MCCARTY M. Studies on the chemical structure of the streptococcal cell wall. I. The identification of a mucopeptide in the cell walls of groups A and A-variant streptococci. J Exp Med. 1961 Jul 1;114:127–140. doi: 10.1084/jem.114.1.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Krause R. M. Experimental approaches to homogenous antibody populations. Factors controlling the occurrence of antibodies with uniform properties. Fed Proc. 1970 Jan-Feb;29(1):59–65. [PubMed] [Google Scholar]
- Lindqvist K., Bauer D. C. Precipitin activity of rabbit macroglobulin antibody. Immunochemistry. 1966 Sep;3(5):373–384. doi: 10.1016/0019-2791(66)90175-3. [DOI] [PubMed] [Google Scholar]
- Osterland C. K., Miller E. J., Karakawa W. W., Krause R. M. Characteristics of streptococcal group-specific antibody isolated from hyperimmune rabbits. J Exp Med. 1966 Apr 1;123(4):599–614. doi: 10.1084/jem.123.4.599. [DOI] [PMC free article] [PubMed] [Google Scholar]