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. 1978 Jul;75(7):3413–3416. doi: 10.1073/pnas.75.7.3413

Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocytic choriomeningitis virus.

J Gresser, L Morel-Maroger, P Verroust, Y Rivière, J C Guillon
PMCID: PMC392787  PMID: 277942

Abstract

Swiss mice infected at birth with lymphocytic choriomeningitis virus develop glomerulonephritis. Injection of potent anti-mouse interferon globulin at the time of viral infection inhibited the development of these renal lesions. We conclude that the production of endogenous interferon by this virus in the first few days of life plays an important role in the pathogenesis of this glomerulonephritis.

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Selected References

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