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. 1985 Apr;82(8):2452–2455. doi: 10.1073/pnas.82.8.2452

An unusual genetic code in nuclear genes of Tetrahymena.

S Horowitz, M A Gorovsky
PMCID: PMC397576  PMID: 3921962

Abstract

We have cloned and partially sequenced two histone H3 genes of Tetrahymena thermophila. The DNA sequences strongly suggest that both genes are active in the vegetatively growing cell. Comparison of the derived amino acid sequences of these two genes with the actual sequence of Tetrahymena histone H3 results in the surprising conclusion that TAA codes for glutamine. This represents the first demonstration of a coding function for this termination codon of the "universal" code. This observation has important implications for the evolution of ciliates and of the genetic code.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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