Skip to main content
PMC home page
Clinical Molecular Pathology logoLink to Clinical Molecular Pathology
. 1996 Apr;49(2):M74–M79. doi: 10.1136/mp.49.2.m74

Nomenclature for proteins: is calprotectin a proper name for the elusive myelomonocytic protein?

M K Fagerhol 1
PMCID: PMC408025  PMID: 16696054

Full text

PDF
M76

Images in this article

M75Image
on p.M75
M76Image
on p.M76
M77Image
on p.M77

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andersson K. B., Sletten K., Berntzen H. B., Dale I., Brandtzaeg P., Jellum E., Fagerhol M. K. The leucocyte L1 protein: identity with the cystic fibrosis antigen and the calcium-binding MRP-8 and MRP-14 macrophage components. Scand J Immunol. 1988 Aug;28(2):241–245. doi: 10.1111/j.1365-3083.1988.tb02437.x. [DOI] [PubMed] [Google Scholar]
  2. Barthe C., Figarella C., Carrère J., Guy-Crotte O. Identification of 'cystic fibrosis protein' as a complex of two calcium-binding proteins present in human cells of myeloid origin. Biochim Biophys Acta. 1991 Feb 22;1096(2):175–177. doi: 10.1016/0925-4439(91)90057-g. [DOI] [PubMed] [Google Scholar]
  3. Berner Berntzen H., Endresen G. K., Fagerhol M. K., Spiechowicz J., Mowinckel P. Calprotectin (the L1 protein) during surgery in patients with rheumatoid arthritis. Scand J Clin Lab Invest. 1991 Nov;51(7):643–650. doi: 10.3109/00365519109104575. [DOI] [PubMed] [Google Scholar]
  4. Berntzen H. B., Fagerhol M. K. L1, a major granulocyte protein: antigenic properties of its subunits. Scand J Clin Lab Invest. 1988 Nov;48(7):647–652. [PubMed] [Google Scholar]
  5. Berntzen H. B., Fagerhol M. K. L1, a major granulocyte protein; isolation of high quantities of its subunits. Scand J Clin Lab Invest. 1990 Nov;50(7):769–774. doi: 10.1080/00365519009091071. [DOI] [PubMed] [Google Scholar]
  6. Brandtzaeg P., Dale I., Fagerhol M. K. Distribution of a formalin-resistant myelomonocytic antigen (L1) in human tissues. II. Normal and aberrant occurrence in various epithelia. Am J Clin Pathol. 1987 Jun;87(6):700–707. doi: 10.1093/ajcp/87.6.700. [DOI] [PubMed] [Google Scholar]
  7. Clark B. R., Kelly S. E., Fleming S. Calgranulin expression and association with the keratinocyte cytoskeleton. J Pathol. 1990 Jan;160(1):25–30. doi: 10.1002/path.1711600107. [DOI] [PubMed] [Google Scholar]
  8. Dale I., Brandtzaeg P. Expression of the epithelial L1 antigen as an immunohistochemical marker of squamous cell carcinoma of the lung. Histopathology. 1989 May;14(5):493–502. doi: 10.1111/j.1365-2559.1989.tb02185.x. [DOI] [PubMed] [Google Scholar]
  9. Dale I., Fagerhol M. K., Naesgaard I. Purification and partial characterization of a highly immunogenic human leukocyte protein, the L1 antigen. Eur J Biochem. 1983 Jul 15;134(1):1–6. doi: 10.1111/j.1432-1033.1983.tb07522.x. [DOI] [PubMed] [Google Scholar]
  10. Edgeworth J. D., Abiose A., Jones B. R. An immunohistochemical analysis of onchocercal nodules: evidence for an interaction between macrophage MRP8/MRP14 and adult Onchocerca volvulus. Clin Exp Immunol. 1993 Apr;92(1):84–92. doi: 10.1111/j.1365-2249.1993.tb05952.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Edgeworth J., Gorman M., Bennett R., Freemont P., Hogg N. Identification of p8,14 as a highly abundant heterodimeric calcium binding protein complex of myeloid cells. J Biol Chem. 1991 Apr 25;266(12):7706–7713. [PubMed] [Google Scholar]
  12. Eggleton P., Gargan R., Fisher D. Rapid method for the isolation of neutrophils in high yield without the use of dextran or density gradient polymers. J Immunol Methods. 1989 Jul 6;121(1):105–113. doi: 10.1016/0022-1759(89)90425-0. [DOI] [PubMed] [Google Scholar]
  13. Eversole L. R., Miyasaki K. T., Christensen R. E. The distribution of the antimicrobial protein, calprotectin, in normal oral keratinocytes. Arch Oral Biol. 1992 Nov;37(11):963–968. doi: 10.1016/0003-9969(92)90068-j. [DOI] [PubMed] [Google Scholar]
  14. Gabrielsen T. O., Brandtzaeg P., Hoel P. S., Dale I. Epithelial distribution of a myelomonocytic antigen LI in relation to cutaneous malignancies and melanocytic naevi. Br J Dermatol. 1988 Jan;118(1):59–67. doi: 10.1111/j.1365-2133.1988.tb01750.x. [DOI] [PubMed] [Google Scholar]
  15. Gabrielsen T. O., Dale I., Brandtzaeg P., Hoel P. S., Fagerhol M. K., Larsen T. E., Thune P. O. Epidermal and dermal distribution of a myelomonocytic antigen (L1) shared by epithelial cells in various inflammatory skin diseases. J Am Acad Dermatol. 1986 Aug;15(2 Pt 1):173–179. doi: 10.1016/s0190-9622(86)70152-7. [DOI] [PubMed] [Google Scholar]
  16. Hessian P. A., Edgeworth J., Hogg N. MRP-8 and MRP-14, two abundant Ca(2+)-binding proteins of neutrophils and monocytes. J Leukoc Biol. 1993 Feb;53(2):197–204. [PubMed] [Google Scholar]
  17. Kelly S. E., Jones D. B., Fleming S. Calgranulin expression in inflammatory dermatoses. J Pathol. 1989 Sep;159(1):17–21. doi: 10.1002/path.1711590107. [DOI] [PubMed] [Google Scholar]
  18. Kunz M., Roth J., Sorg C., Kolde G. Epidermal expression of the calcium binding surface antigen 27E10 in inflammatory skin diseases. Arch Dermatol Res. 1992;284(7):386–390. doi: 10.1007/BF00372067. [DOI] [PubMed] [Google Scholar]
  19. Lagasse E., Clerc R. G. Cloning and expression of two human genes encoding calcium-binding proteins that are regulated during myeloid differentiation. Mol Cell Biol. 1988 Jun;8(6):2402–2410. doi: 10.1128/mcb.8.6.2402. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Miyasaki K. T., Bodeau A. L., Murthy A. R., Lehrer R. I. In vitro antimicrobial activity of the human neutrophil cytosolic S-100 protein complex, calprotectin, against Capnocytophaga sputigena. J Dent Res. 1993 Feb;72(2):517–523. doi: 10.1177/00220345930720020801. [DOI] [PubMed] [Google Scholar]
  21. Murthy A. R., Lehrer R. I., Harwig S. S., Miyasaki K. T. In vitro candidastatic properties of the human neutrophil calprotectin complex. J Immunol. 1993 Dec 1;151(11):6291–6301. [PubMed] [Google Scholar]
  22. Naess-Andresen C. F., Egelandsdal B., Fagerhol M. K. Calcium binding and concomitant changes in the structure and heat stability of calprotectin (L1 protein). Clin Mol Pathol. 1995 Oct;48(5):M278–M284. doi: 10.1136/mp.48.5.m278. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Odink K., Cerletti N., Brüggen J., Clerc R. G., Tarcsay L., Zwadlo G., Gerhards G., Schlegel R., Sorg C. Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature. 1987 Nov 5;330(6143):80–82. doi: 10.1038/330080a0. [DOI] [PubMed] [Google Scholar]
  24. Røseth A. G., Fagerhol M. K., Aadland E., Schjønsby H. Assessment of the neutrophil dominating protein calprotectin in feces. A methodologic study. Scand J Gastroenterol. 1992 Sep;27(9):793–798. doi: 10.3109/00365529209011186. [DOI] [PubMed] [Google Scholar]
  25. Sohnle P. G., Collins-Lech C., Wiessner J. H. Antimicrobial activity of an abundant calcium-binding protein in the cytoplasm of human neutrophils. J Infect Dis. 1991 Jan;163(1):187–192. doi: 10.1093/infdis/163.1.187. [DOI] [PubMed] [Google Scholar]
  26. Steinbakk M., Naess-Andresen C. F., Lingaas E., Dale I., Brandtzaeg P., Fagerhol M. K. Antimicrobial actions of calcium binding leucocyte L1 protein, calprotectin. Lancet. 1990 Sep 29;336(8718):763–765. doi: 10.1016/0140-6736(90)93237-j. [DOI] [PubMed] [Google Scholar]
  27. Tungekar M. F., Heryet A., Gatter K. C. The L1 antigen and squamous metaplasia in the bladder. Histopathology. 1991 Sep;19(3):245–250. doi: 10.1111/j.1365-2559.1991.tb00029.x. [DOI] [PubMed] [Google Scholar]
  28. Wilkinson M. M., Busuttil A., Hayward C., Brock D. J., Dorin J. R., Van Heyningen V. Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues. J Cell Sci. 1988 Oct;91(Pt 2):221–230. doi: 10.1242/jcs.91.2.221. [DOI] [PubMed] [Google Scholar]
  29. Wilson G. B., Jahn T. L., Fonseca J. R. Demonstration of serum protein differences in cystic fibrosis by isoelectric focusing in thin-layer polyacrylamide gels. Clin Chim Acta. 1973 Nov 23;49(1):79–91. doi: 10.1016/0009-8981(73)90346-x. [DOI] [PubMed] [Google Scholar]
  30. van Heyningen V., Hayward C., Fletcher J., McAuley C. Tissue localization and chromosomal assignment of a serum protein that tracks the cystic fibrosis gene. Nature. 1985 Jun 6;315(6019):513–515. doi: 10.1038/315513a0. [DOI] [PubMed] [Google Scholar]

Articles from Clinical Molecular Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES