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. 1979 Dec;76(12):6500–6504. doi: 10.1073/pnas.76.12.6500

Human heterozygosity: a new estimate.

E H McConkey, B J Taylor, D Phan
PMCID: PMC411893  PMID: 293737

Abstract

Several hundred polypeptides from four human diploid fibroblast cell lines were compared by high-resolution two-dimensional polyacrylamide gel electrophoresis and double-label autoradiography under conditions where allelic products that differ by a single charged amino acid would be distinguished. The average heterozygosity represented by this set of gene products appears to be less than 1% for changes involving charged amino acids.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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