Skip to main content
PMC home page
Infection and Immunity logoLink to Infection and Immunity
. 1974 Jul;10(1):72–82. doi: 10.1128/iai.10.1.72-82.1974

Immunity to Candida albicans Induced by Listeria monocytogenes

Shirley Marra 1, Edward Balish 1
PMCID: PMC414959  PMID: 4210334

Abstract

Immunity to Candida albicans was studied in Swiss-Webster white female mice. Lethal and sublethal infections with C. albicans did not enhance immunity to a subsequent Listeria monocytogenes challenge. Mice sensitized to L. monocytogenes and then challenged with C. albicans intravenously were able to reduce the population of C. albicans in their kidneys after being boosted (rechallenged) with L. monocytogenes. However, the acquired cellular immunity so induced was very short-lived. Both C. albicans-sensitized and nonsensitized control mice showed an immediate-type and delayed-type skin test response to the cell wall antigen(s) of C. albicans but not to the cytoplasmic antigen(s). There did not appear to be any correlation between increase in skin test response and progression of the candida infection in mice.

Full text

PDF
82

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ammann A. J., Meuwissen H. J., Good R. A., Hong R. Successful bone marrow transplantation in a patient with humoral and cellular immunity deficiency. Clin Exp Immunol. 1970 Sep;7(3):343–353. [PMC free article] [PubMed] [Google Scholar]
  2. August C. S., Berkel A. I., Levey R. H., Rosen F. S., Kay H. E. Establishment of immunological competence in a child with congenital thymic aplasia by a graft of fetal thymus. Lancet. 1970 May 23;1(7656):1080–1083. doi: 10.1016/s0140-6736(70)92755-8. [DOI] [PubMed] [Google Scholar]
  3. Bird D. C., Sheagren J. N. Evaluation of reticuloendothelial system phagocytic activity during systemic Candida albicans infection in mice. Proc Soc Exp Biol Med. 1970 Jan;133(1):34–37. doi: 10.3181/00379727-133-34401. [DOI] [PubMed] [Google Scholar]
  4. Bryant R. E., Sutcliffe M. C., McGee Z. A. Effect of osmolalities comparable to those of the renal medulla on function of human polymorphonuclear leukocytes. J Infect Dis. 1972 Jul;126(1):1–10. doi: 10.1093/infdis/126.1.1. [DOI] [PubMed] [Google Scholar]
  5. CHERNEW I., BRAUDE A. I. Depression of phagocytosis by solutes in concentrations found in the kidney and urine. J Clin Invest. 1962 Oct;41:1945–1953. doi: 10.1172/JCI104652. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Canales L., Middlemas R. O., 3rd, Louro J. M., South M. A. Immunological observations in chronic mucocutaneous candidiasis. Lancet. 1969 Sep 13;2(7620):567–571. doi: 10.1016/s0140-6736(69)90264-5. [DOI] [PubMed] [Google Scholar]
  7. Collins F. M., Mackaness G. B., Blanden R. V. Infection-immunity in experimental salmonellosis. J Exp Med. 1966 Oct 1;124(4):601–619. doi: 10.1084/jem.124.4.601. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. ELBERG S. S., SCHNEIDER P., FONG J. Cross-immunity between Brucella melitensis and Mycobacterium tuberculosis; intracellular behavior of Brucella melitensis in monocytes from vaccinated animals. J Exp Med. 1957 Oct 1;106(4):545–554. doi: 10.1084/jem.106.4.545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gentry L. O., Remington J. S. Resistance against Cryptococcus conferred by intracellular bacteria and protozoa. J Infect Dis. 1971 Jan;123(1):22–31. doi: 10.1093/infdis/123.1.22. [DOI] [PubMed] [Google Scholar]
  10. Halliburton B. L., Hinsdill R. D. Recall of acquired cellular resistance in mice by antigens from killed Brucella. Infect Immun. 1972 Jan;5(1):42–47. doi: 10.1128/iai.5.1.42-47.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kirkpatrick C. H., Rich R. R., Bennett J. E. Chronic mucocutaneous candidiasis: model-building in cellular immunity. Ann Intern Med. 1971 Jun;74(6):955–978. doi: 10.7326/0003-4819-74-6-955. [DOI] [PubMed] [Google Scholar]
  12. Kirkpatrick C. H., Rich R. R., Graw R. G., Jr, Smith T. K., Mickenberg I., Rogentine G. N. Treatment of chronic mucocutaneous moniliasis by immunologic reconstitution. Clin Exp Immunol. 1971 Dec;9(6):733–748. [PMC free article] [PubMed] [Google Scholar]
  13. LOURIA D. B., BRAYTON R. G. BEHAVIOR OF CANDIDA CELLS WITHIN LEUKOCYTES. Proc Soc Exp Biol Med. 1964 Jan;115:93–98. doi: 10.3181/00379727-115-28840. [DOI] [PubMed] [Google Scholar]
  14. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  15. Lehrer R. I., Cline M. J. Interaction of Candida albicans with human leukocytes and serum. J Bacteriol. 1969 Jun;98(3):996–1004. doi: 10.1128/jb.98.3.996-1004.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Lehrer R. I. Measurement of candidacidal activity of specific leukocyte types in mixed cell populations I. Normal, myeloperoxidase-deficient, and chronic granulomatous disease neutrophils. Infect Immun. 1970 Jul;2(1):42–47. doi: 10.1128/iai.2.1.42-47.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. MACKANESS G. B. THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE. J Exp Med. 1964 Jul 1;120:105–120. doi: 10.1084/jem.120.1.105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Mackaness G. B., Blanden R. V. Cellular immunity. Prog Allergy. 1967;11:89–140. [PubMed] [Google Scholar]
  19. Mackaness G. B. The influence of immunologically committed lymphoid cells on macrophage activity in vivo. J Exp Med. 1969 May 1;129(5):973–992. doi: 10.1084/jem.129.5.973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Mackaness G. B. The relationship of delayed hypersensitivity to acquired cellular resistance. Br Med Bull. 1967 Jan;23(1):52–54. doi: 10.1093/oxfordjournals.bmb.a070516. [DOI] [PubMed] [Google Scholar]
  21. Mardon D. N., Balish E. Modifications in a French pressure cell-laboratory press system. Appl Microbiol. 1969 May;17(5):777–777. doi: 10.1128/am.17.5.777-777.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Ruskin J., Remington J. S. Immunity and intracellular infection: resistance to bacteria in mice infected with a protozoan. Science. 1968 Apr 5;160(3823):72–74. doi: 10.1126/science.160.3823.72. [DOI] [PubMed] [Google Scholar]
  23. Salvin S. B., Cheng S. L. Lymphoid Cells in Delayed Hypersensitivity II. In Vitro Phagocytosis and Cellular Immunity. Infect Immun. 1971 Apr;3(4):548–552. doi: 10.1128/iai.3.4.548-552.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Savage D. C., Dubos R. J. Localization of indigenous yeast in the murine stomach. J Bacteriol. 1967 Dec;94(6):1811–1816. doi: 10.1128/jb.94.6.1811-1816.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES