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. 1974 Jul;10(1):284–285. doi: 10.1128/iai.10.1.284-285.1974

Influence of Molecular Weights of Bacteriophage φ6 Double-Stranded Ribonucleic Acids on Interferon Induction 1

W J Kleinschmidt 1,2, J L Van Etten 1,2, A K Vidaver 1,2
PMCID: PMC414992  PMID: 4842130

Abstract

The interferon-inducing capabilities of the three molecular segments of bacteriophage φ6 double-stranded ribonucleic acid increased with increasing molecular weight.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arnott S., Fuller W., Hodgson A., Prutton I. Molecular conformations and structure transitions of RNA complementary helices and their possible biological significance. Nature. 1968 Nov 9;220(5167):561–564. doi: 10.1038/220561a0. [DOI] [PubMed] [Google Scholar]
  2. Black D. R., Eckstein F., Hobbs J. B., Sternbach H., Merigan T. C. The antiviral activity of certain thiophosphate and 2'-chloro substituted polynucleotide homopolymer duplexes. Virology. 1972 May;48(2):537–545. doi: 10.1016/0042-6822(72)90064-5. [DOI] [PubMed] [Google Scholar]
  3. Colby C., Chamberlin M. J. The specificity of interferon induction in chick embryo cells by helical RNA. Proc Natl Acad Sci U S A. 1969 May;63(1):160–167. doi: 10.1073/pnas.63.1.160. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Colby C., Stollar B. D., Simon M. I. Interferon induction: DNA-RNA hybrid or double stranded RNA? Nat New Biol. 1971 Feb 10;229(6):172–174. doi: 10.1038/newbio229172a0. [DOI] [PubMed] [Google Scholar]
  5. Kleinschmidt W. J. Biochemistry of interferon and its inducers. Annu Rev Biochem. 1972;41(10):517–542. doi: 10.1146/annurev.bi.41.070172.002505. [DOI] [PubMed] [Google Scholar]
  6. Kleinschmidt W. J., Douthart R. J., Murphy E. B. Interferon production by T4 coliphage. Nature. 1970 Oct 3;228(5266):27–30. doi: 10.1038/228027a0. [DOI] [PubMed] [Google Scholar]
  7. Lampson G. P., Field A. K., Tytell A. A., Nemes M. M., Hilleman M. R. Relationship of molecular size of rIn:rCn (poly I:C) to induction of interferon and host resistance. Proc Soc Exp Biol Med. 1970 Dec;135(3):911–916. doi: 10.3181/00379727-135-35169. [DOI] [PubMed] [Google Scholar]
  8. Milman G., Langridge R., Chamberlin M. J. The structure of a DNA-RNA hybrid. Proc Natl Acad Sci U S A. 1967 Jun;57(6):1804–1810. doi: 10.1073/pnas.57.6.1804. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Niblack J. F., McCreary M. B. Relationship of biological activities of poly I-poly C to homopolymer molecular weights. Nat New Biol. 1971 Sep 8;233(36):52–53. doi: 10.1038/newbio233052a0. [DOI] [PubMed] [Google Scholar]
  10. Semancik J. S., Vidaver A. K., Van Etten J. L. Characterization of segmented double-helical RNA from bacteriophage phi6. J Mol Biol. 1973 Aug 25;78(4):617–625. doi: 10.1016/0022-2836(73)90283-0. [DOI] [PubMed] [Google Scholar]
  11. Steward D. L., Herndon W. C., Jr, Schell K. R. Influence of 2'-O-acetylation on the antiviral activity of polyribonucleotides. Biochim Biophys Acta. 1972 Mar 14;262(2):227–232. doi: 10.1016/0005-2787(72)90237-7. [DOI] [PubMed] [Google Scholar]
  12. Van Etten J. L., Vidaver A. K., Koski R. K., Burnett J. P. Base composition and hybridization studies of the three double-stranded RNA segments of bacteriophage phi 6. J Virol. 1974 Jun;13(6):1254–1262. doi: 10.1128/jvi.13.6.1254-1262.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]

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