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. 1976 Oct;14(4):1087–1096. doi: 10.1128/iai.14.4.1087-1096.1976

Electron microscopic study on the interaction between normal guinea pig peritoneal macrophages and Coxiella burnetii.

R A Kishimoto, B J Veltri, P G Canonico, F G Shirey, J S Walker
PMCID: PMC415496  PMID: 825466

Abstract

An electron microscopic study was conducted to explore the interaction between normal guinea pig peritoneal macrophages and phase I and II Coxeilla burnetii previously treated with either normal or immune serum. A comparison was made on the efficiency of phagocytosis and subsequent killing of rickettsiae by macrophages. Both phases of rickettsiae previously treated with normal serum multiplied within phagosomes after phagocytosis with resultant destruction of macrophages. In contrast, suspending rickettsiae in immune serum rendered them more susceptible to phagocytosis and potentiated their destruction within macrophages.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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