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. 1970 Jun;1(6):600–603. doi: 10.1128/iai.1.6.600-603.1970

Demonstration in Tissue Culture of Lymphocyte-Mediated Immunity to Tuberculosis

Ronald J Patterson 1, Guy P Youmans 1
PMCID: PMC415948  PMID: 16557782

Abstract

We have shown that splenic lymphocytes from mice immunized with viable attenuated mycobacterial cells (H37Ra) or ribonucleic acid prepared from these cells will bring about inhibition of multiplication of virulent tubercle bacilli (H37Rv) within normal mouse peritoneal macrophages in tissue culture. Apparently these lymphocytes, when stimulated with viable virulent tubercle bacilli, elaborate a filterable substance(s) which is responsible for this intracellular growth inhibitory effect.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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