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. 1971 Jul;4(1):79–84. doi: 10.1128/iai.4.1.79-84.1971

Cross-Protective Antigens of Group A Streptococci Types 3 and 31 and Types 46 and 51

William K Harrell 1, Helen Ashworth 1, Robert E Davis II 1
PMCID: PMC416267  PMID: 5005288

Abstract

Reciprocal cross-protective antigens have been demonstrated between types 3 and 31 cocci, and one-way cross-protective antigens have been demonstrated between types 46 and 51 cocci. The reciprocal cross-protective antigen of types 3 and 31 is distinct from the specific M protein of either type. In the one-way cross relationship, type 46 cocci contain both type 46 and type 51 M proteins and therefore stimulate protective antibodies against both types. Type 51 cultures contain only the homologous M antigen. These relationships were demonstrated by capillary precipitin tests, indirect bactericidal tests, and in agar-gel diffusion patterns. The practical significance of these relationships in the serological typing of group A streptococci is discussed along with their possible role in immunity to streptococcal infections in man.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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