Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1976 Mar;13(3):995–997. doi: 10.1128/iai.13.3.995-997.1976

Evaluation of adenosine deaminase and other purine salvage pathway enzymes in horses with combined immunodeficiency.

T C McGuire, B Pollara, J J Moore, M J Poppie
PMCID: PMC420706  PMID: 818021

Abstract

Foals with combined immunodeficiency had normal levels of purine salvage pathway enzymes, including adenosine deaminase, nucleoside phosphorylase, and xanthine oxidase.

Full text

PDF
997

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andrews P. Estimation of the molecular weights of proteins by Sephadex gel-filtration. Biochem J. 1964 May;91(2):222–233. doi: 10.1042/bj0910222. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BRADY T. G., O'DONOVAN C. I. A STUDY OF THE TISSUE DISTRIBUTION OF ADENOSINE DEAMINASE IN SIX MAMMAL SPECIES. Comp Biochem Physiol. 1965 Jan;14:101–120. doi: 10.1016/0010-406x(65)90011-3. [DOI] [PubMed] [Google Scholar]
  3. Bartholomew W. R., Provost T. T. Letter: Combined-immunodeficiency disease with normal erythrocyte A.D.A. Lancet. 1974 Apr;1(7859):678–678. doi: 10.1016/s0140-6736(74)93228-0. [DOI] [PubMed] [Google Scholar]
  4. Creagan R. P., Tischfield J. A., Nichols E. A., Ruddle F. H. Letter: Autosomal assignment of the gene for the form of adenosine deaminase which is deficient in patients with combined immunodeficiency syndrome. Lancet. 1973 Dec 22;2(7843):1449–1449. doi: 10.1016/s0140-6736(73)92850-x. [DOI] [PubMed] [Google Scholar]
  5. Giblett E. R., Anderson J. E., Cohen F., Pollara B., Meuwissen H. J. Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. Lancet. 1972 Nov 18;2(7786):1067–1069. doi: 10.1016/s0140-6736(72)92345-8. [DOI] [PubMed] [Google Scholar]
  6. Hopkinson D. A., Cook P. J., Harris H. Further data on the adenosine deaminase (ADA) polymprphism and a report of a new phenotype. Ann Hum Genet. 1969 May;32(4):361–367. doi: 10.1111/j.1469-1809.1969.tb00087.x. [DOI] [PubMed] [Google Scholar]
  7. McGuire T. C., Banks K. L., Poppie M. J. Combined immunodeficiency in horses: characterization of the lymphocyte defect. Clin Immunol Immunopathol. 1975 Mar;3(4):555–566. doi: 10.1016/0090-1229(75)90080-x. [DOI] [PubMed] [Google Scholar]
  8. McGuire T. C., Poppie M. J., Banks K. L. Combined (B- and T-lymphocyte) immunodeficiency: a fatal genetic disease in Arabian foals. J Am Vet Med Assoc. 1974 Jan 1;164(1):70–76. [PubMed] [Google Scholar]
  9. McGuire T. C., Poppie M. J. Hypogammaglobulinemia and thymic hypoplasia in horses: a primary combined immunodeficiency disorder. Infect Immun. 1973 Aug;8(2):272–277. doi: 10.1128/iai.8.2.272-277.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Parkman R., Gelfand E. W., Rosen F. S., Sanderson A., Hirschhorn R. Severe combined immunodeficiency and adenosine deaminase deficiency. N Engl J Med. 1975 Apr 3;292(14):714–719. doi: 10.1056/NEJM197504032921402. [DOI] [PubMed] [Google Scholar]
  11. Pickering R. J., Pollara B., Meuwissen H. J. Workshop on severe combined immunological deficiency disease and adenosine deaminase deficiency. Albany, New York, on October 1, 1973. Clin Immunol Immunopathol. 1974 Nov;3(2):301–303. doi: 10.1016/0090-1229(74)90016-6. [DOI] [PubMed] [Google Scholar]
  12. Scott C. R., Chen S. H., Giblett E. R. Detection of the carrier state in combined immunodeficiency disease associated with adenosine deaminase deficiency. J Clin Invest. 1974 Apr;53(4):1194–1196. doi: 10.1172/JCI107658. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES