Abstract
Thirty-four strains of Streptococcus mutans whose antigenic or genetic positions were unclear or unknown with respect to the serological scheme of Bratthall (1970) and Perch et al. (1974), or the genetic (deoxyribonucleic acid base sequence homology) scheme of Coykendall were analyzed to clarify their relationship to previously well-characterized strains. Strain OMZ175 of the "new" serotype f was genetically homologous with strains of S. mutans subsp. mutans. Strains of the "new" serotype g were homologous with serotype d strains (S. mutans subsp. sobrinus). Strains isolated from wild rats constituted a new genetic group but carried the c antigen. Thus, strains within a "genospecies" (subspecies) of S. mutans may not always carry a unique or characteristic antigen. We suggest that the existence of multiple serotypes within subspecies represents antigenic variation and adaptations to hosts.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bratthall D. Demonstration of five serological groups of streptococcal strains resembling Streptococcus mutans. Odontol Revy. 1970;21(2):143–152. [PubMed] [Google Scholar]
- Bratthall D., Gibbons R. J. Antigenic variation of Streptococcus mutans colonizing gnotobiotic rats. Infect Immun. 1975 Dec;12(6):1231–1236. doi: 10.1128/iai.12.6.1231-1236.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bratthall D. Immunodiffusion studies on the serological specificity of streptococci resembling Streptococcus mutans. Odontol Revy. 1969;20(3):231–243. [PubMed] [Google Scholar]
- Bratthall D. Immunofluorescent identification of Streptococcus mutans. Odontol Revy. 1972;23(2):181–196. [PubMed] [Google Scholar]
- Bratthall D., Pettersson B. M. Common and unique antigens of Streptococcus mutants. J Dent Res. 1976 Jan;55:A60–A64. doi: 10.1177/002203457605500123011. [DOI] [PubMed] [Google Scholar]
- Carlsson J. A numerical taxonomic study of human oral streptococci. Odontol Revy. 1968;19(2):137–160. [PubMed] [Google Scholar]
- Coykendall A. L. Base composition of deoxyribonucleic acid isolated from cariogenic streptococci. Arch Oral Biol. 1970 Apr;15(4):365–368. doi: 10.1016/0003-9969(70)90063-4. [DOI] [PubMed] [Google Scholar]
- Coykendall A. L. Four types of Streptococcus mutans based on their genetic, antigenic and biochemical characteristics. J Gen Microbiol. 1974 Aug;83(2):327–338. doi: 10.1099/00221287-83-2-327. [DOI] [PubMed] [Google Scholar]
- Coykendall A. L. Genetic heterogeneity in Streptococcus mutans. J Bacteriol. 1971 Apr;106(1):192–196. doi: 10.1128/jb.106.1.192-196.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Coykendall A. L., Specht P. A., Samol H. H. Streptococcus mutans in a wild, sucrose-eating rat population. Infect Immun. 1974 Jul;10(1):216–219. doi: 10.1128/iai.10.1.216-219.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Denhardt D. T. A membrane-filter technique for the detection of complementary DNA. Biochem Biophys Res Commun. 1966 Jun 13;23(5):641–646. doi: 10.1016/0006-291x(66)90447-5. [DOI] [PubMed] [Google Scholar]
- Edwardsson S. Characteristics of caries-inducing human streptococci resembling Streptococcus mutans. Arch Oral Biol. 1968 Jun;13(6):637–646. doi: 10.1016/0003-9969(68)90142-8. [DOI] [PubMed] [Google Scholar]
- FITZGERALD R. J., JORDAN H. V., STANLEY H. R. Experimental caries and gingival pathologic changes in the gnotobiotic rat. J Dent Res. 1960 Sep-Oct;39:923–935. doi: 10.1177/00220345600390052701. [DOI] [PubMed] [Google Scholar]
- Guggenheim B. Streptococci of dental plaques. Caries Res. 1968;2(2):147–163. doi: 10.1159/000259553. [DOI] [PubMed] [Google Scholar]
- Guy E. M. Characteristics of some extra-cellular, polysaccharide-producing, oral streptococci from Tokelauan Islanders. N Z Dent J. 1974 Apr;70(320):118–125. [PubMed] [Google Scholar]
- MARMUR J., DOTY P. Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. J Mol Biol. 1962 Jul;5:109–118. doi: 10.1016/s0022-2836(62)80066-7. [DOI] [PubMed] [Google Scholar]
- Perch B., Kjems E., Ravn T. Biochemical and serological properties of Streptococcus mutans from various human and animal sources. Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Jun;82(3):357–370. doi: 10.1111/j.1699-0463.1974.tb02338.x. [DOI] [PubMed] [Google Scholar]
- RANTZ L. A., RANDALL E. Use of autoclaved extracts of hemolytic streptococci for serological grouping. Stanford Med Bull. 1955 May;13(2):290–291. [PubMed] [Google Scholar]