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. 1977 Jul;17(1):227–230. doi: 10.1128/iai.17.1.227-230.1977

Suppressive effect of cyclophosphamide on the T-cell system in chickens.

J M Sharma, L F Lee
PMCID: PMC421104  PMID: 301860

Abstract

Neonatal administration of 16 mg of cyclophosphamide in inbred chickens resulted in a transient, but profound, deficiency in the in vitro proliferative response of spleen cells. Functional T-cell deficiency was accompanied by a marked morphological degeneration in the thymus and thymus-dependent areas in the spleen.

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Selected References

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