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. 1977 Oct;18(1):165–172. doi: 10.1128/iai.18.1.165-172.1977

Genetic studies on Neisseria gonorrhoeae from disseminated gonococcal infections.

L W Mayer, G K Schoolnik, S Falkow
PMCID: PMC421209  PMID: 409684

Abstract

Isolates from uncomplicated and disseminated gonococcal infections were analyzed by using deoxyribonucleic acid-mediated transformation. Most pairs of auxotrophs could recombine, producing independent transformants. When the constellation of arginine (Arg), hypoxanthine (Hyx), and uracil (Ura) requirements was present in donor and recipient, no recombination for these traits could be detected. Except for Arg to Hyx, no linkage between Arg, Hyx, Ura, penicillin G sensitivity, and serum resistance could be demonstrated. Some distant linkage of Ura to nalidixic acid and rifampin resistances was found. The data show that the traits associated with disseminated gonococcal infection strains are not closely linked but are identical in all strains, indicating a common origin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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