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. 1972 Jan;5(1):31–34. doi: 10.1128/iai.5.1.31-34.1972

Experimental Oral Immunization with L-Forms of Vibrio cholerae

S C Agarwal a,1, N K Ganguly a
PMCID: PMC422316  PMID: 4656355

Abstract

It has been found that oral administration of lysates of L-forms of Vibrio cholerae are antigenic and capable of eliciting an early and high coproantibody response. The L-forms of V. cholerae did not produce any booster effect. Coproantibody rise persists to significant levels even six weeks after oral immunization. L-form lysates of V. cholerae also produce a considerable rise of circulating antibodies and these persist in significantly high titers up to six weeks.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agarwal S. C., Ganguly N. K. Agglutinin and vibriocidal responses of L forms of Vibrio cholerae and El tor. Indian J Med Res. 1971 Jun;59(6):866–872. [PubMed] [Google Scholar]
  2. Bhattacharya P., Mukerjee S. Further studies on the development of a live oral cholera vaccine. J Hyg (Lond) 1968 Jun;66(2):307–318. doi: 10.1017/s0022172400041164. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bhattacharya P., Narayanaswami A., Mukerjee S. Production of antitoxic immunity by live oral cholera vaccine. J Bacteriol. 1968 Jan;95(1):255–256. doi: 10.1128/jb.95.1.255-256.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. FRETER R. Coproantibody and bacterial antagonism as protective factors in experimental enteric cholera. J Exp Med. 1956 Sep 1;104(3):419–426. doi: 10.1084/jem.104.3.419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. FRETER R., GANGAROSA E. J. ORAL IMMUNIZATION AND PRODUCTION OF COPROANTIBODY IN HUMAN VOLUNTEERS. J Immunol. 1963 Dec;91:724–729. [PubMed] [Google Scholar]
  6. Felsenfeld O., Greer W. E. Vibriocidal activity, immune globulin producing cells and immune globulin levels in Theropithecus gelada after administration of a vibrio cholerae antigen. Immunology. 1968 Mar;14(3):319–324. [PMC free article] [PubMed] [Google Scholar]
  7. JENKIN C. R., ROWLEY D. The importance of antibody in the prevention of experimental cholera in rabbits. Br J Exp Pathol. 1960 Feb;41:24–30. [PMC free article] [PubMed] [Google Scholar]
  8. KOSHLAND M. E., BURROWS W. Quantitative studies of the relationship between fecal and serum antibody. J Immunol. 1950 Jul;65(1):93–103. [PubMed] [Google Scholar]
  9. MELNICK J. L., KAPLAN A. S. Quantitative studies of the virus-host relationship in chimpanzees after inapparent infection with Coxsackie viruses. I. The virus carrier state and the development of neutralizing antibodies. J Exp Med. 1953 Mar;97(3):367–400. doi: 10.1084/jem.97.3.367. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Sanyal S. C., Mukerjee S. Live oral cholera vaccine: report of a trial on human volunteer subjects. Bull World Health Organ. 1969 Apr;40(4):503–511. [PMC free article] [PubMed] [Google Scholar]

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