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. 1973 Apr;7(4):600–603. doi: 10.1128/iai.7.4.600-603.1973

Immunity to Chlamydial Infections of the Eye V. Passive Transfer of Antitrachoma Antibodies to Owl Monkeys

Neil S Orenstein 1, J Dennis Mull 1, Sumner E Thompson III 1
PMCID: PMC422730  PMID: 4357603

Abstract

Previous studies have shown that owl monkeys which have had a trachoma agent infection were subsequently highly resistant to challenge by both homologous and heterologous organisms. In the present study, passive transfer of owl monkey serum containing antitrachoma antibody from immune monkeys did not protect recipient monkeys from infectious challenge with homologous trachoma. Antibody was not detectable in eye secretions of the recipient monkeys until the intensity of infection was waning, suggesting but not proving that local antibody synthesis rather than simple transudation of serum antibody occurs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bell S. D., Fraser C. E. Experimental trachoma in owl monkeys. Am J Trop Med Hyg. 1969 Jul;18(4):568–572. doi: 10.4269/ajtmh.1969.18.568. [DOI] [PubMed] [Google Scholar]
  2. Elliff J. E. A method of corneal suture removal. Am J Ophthalmol. 1967 Feb;63(2):346–347. doi: 10.1016/0002-9394(67)91562-0. [DOI] [PubMed] [Google Scholar]
  3. MURRAY E. S., BELL S. D., Jr, HANNA A. T., NICHOLS R. L., SNYDER J. C. Studies on trachoma. 1. Isolation and identification of strains of elementary bodies from Saudi Arabia and Egypt. Am J Trop Med Hyg. 1960 Mar;9:116–124. [PubMed] [Google Scholar]
  4. NICHOLS R. L., McCOMB D. E. Immunofluorescent studies with trachoma and related antigens. J Immunol. 1962 Oct;89:545–554. [PubMed] [Google Scholar]
  5. Nichols R. L., Bobb A. A., Haddad N. A., McComb D. E. Immunofluorescent studies of the microbiologic epidemiology of trachoma in Saudi Arabia. Am J Ophthalmol. 1967 May;63(5 Suppl):1372–1408. doi: 10.1016/0002-9394(67)94123-2. [DOI] [PubMed] [Google Scholar]
  6. Watson R. R., Mull J. D., MacDonald A. B., Thompson S. E., 3rd, Bear S. E. Immunity to chlamydial infections of the eye. II. Studies of passively transferred serum antibody in resistance to infection with guinea pig inclusion conjunctivitis. Infect Immun. 1973 Apr;7(4):597–599. doi: 10.1128/iai.7.4.597-599.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]

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