Skip to main content
PMC home page
Infection and Immunity logoLink to Infection and Immunity
. 1973 Jun;7(6):973–980. doi: 10.1128/iai.7.6.973-980.1973

Isolation and Characterization of an Avian Adenovirus-Associated Virus

Vance J Yates a,1, Abla M El Mishad a, Kenneth J McCormick a, John J Trentin a
PMCID: PMC422790  PMID: 4351971

Abstract

An 18- to 20-nm virus particle was isolated from the Olson strain of quail bronchitis, an avian adenovirus. On density gradient separation the small virions were primarily found at densities of 1.39 and 1.42 g/cm3. The majority of the infectious particles were at the heavier density. The virus had a hexagonal outline and contained single-stranded deoxyribonucleic acid. It was resistant to heating at 56 C for more than an hour and was not inactivated by treatment with chloroform or low pH. Purified virus did not agglutinate erythrocytes of various avian and mammalian species. Replication of the small particles occurred either in chicken embryos or in cultures of embryo kidney cells coinfected with an adenovirus helper. Antigenically the virus was distinct from the adeno-associated viruses types 1, 2, 3, and 4. The virus is the avian equivalent of the adeno-associated viruses of primates and lower animals.

Full text

PDF
977

Images in this article

975Image
on p.975
976Image
on p.976
977Image
on p.977
979Image
on p.979

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALMEIDA J., CINADER B., HOWATSON A. THE STRUCTURE OF ANTIGEN-ANTIBODY COMPLEXES. A STUDY BY ELECTRON MICROSCOPY. J Exp Med. 1963 Sep 1;118:327–340. doi: 10.1084/jem.118.3.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Anderson J., McCormick K. J., Stenback W. A., Trentin J. J. A plaque assay for chick-embryo-lethal-orphan (CELO) virus. Proc Soc Exp Biol Med. 1971 Feb;136(2):499–502. doi: 10.3181/00379727-136-35297. [DOI] [PubMed] [Google Scholar]
  3. Archetti I., Bereczky E., Bocciarelli D. S. A small virus associated with the simian adenovirus SV11. Virology. 1966 Aug;29(4):671–675. doi: 10.1016/0042-6822(66)90291-1. [DOI] [PubMed] [Google Scholar]
  4. FELDMAN H. A., WANG S. S. Sensitivity of various viruses to chloroform. Proc Soc Exp Biol Med. 1961 Apr;106:736–738. doi: 10.3181/00379727-106-26459. [DOI] [PubMed] [Google Scholar]
  5. HAMPARIAN V. V., HILLEMAN M. R., KETLER A. Contributions to characterization and classification of animal viruses. Proc Soc Exp Biol Med. 1963 Apr;112:1040–1050. doi: 10.3181/00379727-112-28247. [DOI] [PubMed] [Google Scholar]
  6. Henle G., Henle W. Immunofluorescence in cells derived from Burkitt's lymphoma. J Bacteriol. 1966 Mar;91(3):1248–1256. doi: 10.1128/jb.91.3.1248-1256.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hoggan M. D. Adenovirus associated viruses. Prog Med Virol. 1970;12:211–239. [PubMed] [Google Scholar]
  8. Hoggan M. D., Blacklow N. R., Rowe W. P. Studies of small DNA viruses found in various adenovirus preparations: physical, biological, and immunological characteristics. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1467–1474. doi: 10.1073/pnas.55.6.1467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Laver W. G., Younghusband H. B., Wrigley N. G. Purification and properties of chick embryo lethal orphan virus (an avian adenovirus). Virology. 1971 Sep;45(3):598–614. doi: 10.1016/0042-6822(71)90175-9. [DOI] [PubMed] [Google Scholar]
  10. Luchsinger E., Strobbe R., Wellemans G., Dekegel D., Sprecher-Goldberger S. Haemagglutinating adeno-associated virus (AAV) in association with bovine adenovirus type 1. Brief report. Arch Gesamte Virusforsch. 1970;31(3):390–392. doi: 10.1007/BF01253774. [DOI] [PubMed] [Google Scholar]
  11. Mayor H. D., Ito M., Jordan L. E., Melnick L. Morphological studies on the replication of a defective satellite virus and its helper adenovirus. J Natl Cancer Inst. 1967 Jun;38(6):805–820. [PubMed] [Google Scholar]
  12. Mayor H. D., Jamison R. M., Jordan L. E., Melnick J. L. Structure and Composition of a Small Particle Prepared from a Simian Adenovirus. J Bacteriol. 1965 Jul;90(1):235–242. doi: 10.1128/jb.90.1.235-242.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Mayor H. D., Melnick J. L. Small deoxyribonucleic acid-containing viruses (picodnavirus group). Nature. 1966 Apr 16;210(5033):331–332. doi: 10.1038/210331a0. [DOI] [PubMed] [Google Scholar]
  14. McCormick K. J., Van Hoosier G. L., Jr Attempts to find human adenovirus type-12 tumor antigens in human tumors. J Natl Cancer Inst. 1968 Feb;40(2):255–261. [PubMed] [Google Scholar]
  15. McFerran J. B., Gordon W. A., Taylor S. M., McParland P. J. Isolation of viruses from 94 flocks of fowls with respiratory disease. Res Vet Sci. 1971 Nov;12(6):565–569. doi: 10.1016/S0034-5288(18)34110-9. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Parks W. P., Melnick J. L., Rongey R., Mayor H. D. Physical assay and growth cycle studies of a defective adeno-satellite virus. J Virol. 1967 Feb;1(1):171–180. doi: 10.1128/jvi.1.1.171-180.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Scott M., McFerran J. B. Isolation of adenoviruses from turkeys. Avian Dis. 1972 Jan-Mar;16(2):413–420. [PubMed] [Google Scholar]
  18. Smith K. O., Gehle W. D., Thiel J. F. Properties of a small virus associated with adenovirus type 4. J Immunol. 1966 Dec;97(6):754–766. [PubMed] [Google Scholar]
  19. Stenback W. A., Van Hoosier G. L., Jr, Trentin J. J. Biophysical, biological, and cytochemical features of a virus associated with transplantable hamster tumors. J Virol. 1968 Oct;2(10):1115–1121. doi: 10.1128/jvi.2.10.1115-1121.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Sugimura T., Yanagawa R. Effect of sodium desoxycholate on infectious canine hepatitis virus, and an additional description of a small associated virus. Jpn J Vet Res. 1968 Mar;16(1):1–12. [PubMed] [Google Scholar]
  21. YATES V. J., FRY D. E. Observations on a chicken embryo lethal orphan (CELO) virus. Am J Vet Res. 1957 Jul;18(68):657–660. [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES