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. 1974 Sep;10(3):430–436. doi: 10.1128/iai.10.3.430-436.1974

Stimulation of Peripheral Blood Lymphocytes by Herpes Simplex Virus in Vitro

M Scriba 1
PMCID: PMC422971  PMID: 4372170

Abstract

A method for stimulating sensitized lymphocytes by inactivated herpes simplex virus was established by using cultures of washed whole blood cells. The development of the immune response of herpes simplex virus-infected guinea pigs was examined at different times in the 4-month period after infection. Humoral and cellular immune responses were compared in individual animals by measuring lymphocyte stimulation ratios and neutralizing serum antibodies.

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Selected References

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