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. 1974 Oct;10(4):695–699. doi: 10.1128/iai.10.4.695-699.1974

Effect of Development and Aging on the Response of Canine Lymphocytes to Phytohemagglutinin

Jay D Gerber 1, Albert L Brown 1
PMCID: PMC423008  PMID: 4547742

Abstract

The stage of development and age were found to effect the responsiveness of dog T-lymphocytes to phytohemagglutinin. T-lymphocytes from beagles 0 to 4 weeks of age showed significantly less response to phytohemagglutinin (P < 0.001) than T-lymphocytes from these same dogs at 6 to 12 weeks of age. Peak response to phytohemagglutinin occurred between 6 weeks to 6 months of age, after which there was a significant correlation (P < 0.02) between increase in age and decrease in phytohemagglutinin responsiveness.

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Selected References

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