Abstract
By time-lapse, phase-contrast cinemicrography of sensory nerve fibers of young mice, isolated with their originating spinal ganglia in nutrient solution, the postulated peristaltic surface drive of the cellulifugal propulsion of the semisolid axonal column at a rate of the order of 1 mm/day (1 μm/min) could be verified and quantitatively analyzed. The pulse waves follow each other at about 30-min intervals, regardless of whether the continuity of the axon is preserved or disrupted by degenerative fragmentation. Even when the axonal flow is obstructed, surface peristalsis continues.
Keywords: time-lapse phase-contrast cinemicrography
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- Weiss P. A. Neuronal dynamics and axonal flow. V. The semisolid state of the moving axonal column. Proc Natl Acad Sci U S A. 1972 Mar;69(3):620–623. doi: 10.1073/pnas.69.3.620. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Weiss P., Taylor A. C., Pillai P. A. The Nerve Fiber as a System in Continuous Flow: Microcinematographic and Electronmicroscopic Demonstrations. Science. 1962 Apr 27;136(3513):330–330. doi: 10.1126/science.136.3513.330. [DOI] [PubMed] [Google Scholar]