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. 1972 Sep;69(9):2537–2541. doi: 10.1073/pnas.69.9.2537

Double-Stranded Regions in Heterogeneous Nuclear RNA from Hela Cells

Warren Jelinek 1, James E Darnell 1
PMCID: PMC426983  PMID: 4506771

Abstract

Heterogeneous nuclear RNA from HeLa cells contains double-stranded regions that arise by base pairing of complementary sequences that exist as parts of the same molecule (intramolecular base pairing). When denatured, the RNA sequences that form the double-stranded regions hybridize rapidly to HeLa cell DNA, suggesting that they are transcribed from reiterated sites in the genome. The messenger RNA does not contain the same class or amount of double-stranded RNA regions found in heterogeneous nuclear RNA.

Keywords: messenger RNA, intramolecular base pairing, RNase resistance

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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