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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1973 Nov;70(11):3072–3076. doi: 10.1073/pnas.70.11.3072

Size and Structure of Yeast Chromosomal DNA

Thomas D Petes 1,*, Breck Byers 1, Walton L Fangman 1
PMCID: PMC427172  PMID: 4594033

Abstract

Electron microscopic analysis indicates that yeast nuclear DNA can be isolated as linear molecules ranging in size from 50 μm (1.2 × 108 daltons) to 355 μm (8.4 × 108 daltons). Analysis indicates the data is consistent with the hypothesis that each yeast chromosome contains a single, linear DNA duplex. Mitochondrial DNA molecules have a contour length of 21 ± 2 μm and are mostly linear.

Keywords: electron microscopy, mitochondrial DNA, linear DNA

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Selected References

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