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Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1975 Jul;8(1):107–109. doi: 10.1128/aac.8.1.107

New Method for Susceptibility Testing with Antifungal Agents

Gerald Wagner 1, Smith Shadomy 1, Larry D Paxton 1, Ana Espinel-Ingroff 1
PMCID: PMC429269  PMID: 1164004

Abstract

A new method for the determination of minimal inhibitory and fungicidal concentrations of antifungal agents for filamentous fungi is described. 5-Fluorocytosine (5-FC) was used as a representative agent and was tested against the following genera: Allescheria, Aspergillus, Cladosporium, Fonsecaea, and Phialophora. 5-FC was found to be inhibitory but not fungicidal for many of the fungi tested, including eight of clinical origin.

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