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. 1976 Mar;9(3):465–469. doi: 10.1128/aac.9.3.465

A New Actinomycin Complex Produced by a Micromonospora Species: Fermentation, Isolation, and Characterization

G H Wagman a, J A Marquez a, P D Watkins a,1, F Gentile a, A Murawski a, M Patel a, M J Weinstein a
PMCID: PMC429553  PMID: 56917

Abstract

A species of Micromonospora, Micromonospora floridensis NRRL 8020, has been found to produce an actinomycin complex consisting of at least 25 active components. After solvent extraction of the complex, separation of the individual components was carried out by preparative thin-layer chromatography. Hydrolysis and subsequent electrophoretic and chromatographic identification of the amino acid content of each of the isolated components have shown differences from known actinomycins, and the probability exists that these contain a number of amino or imino acids not previously found in other members of this group of antibiotics.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. KATZ E., PUGH L. H. Variations on a theme. The actinomycins. Appl Microbiol. 1961 May;9:263–267. doi: 10.1128/am.9.3.263-267.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]

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