Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1976 Jul;10(1):164–172. doi: 10.1128/aac.10.1.164

Acute Diffuse Interstitial Nephritis Related to Chemotherapy of Tuberculosis

William J Stone *, James A Waldron , John H Dixon Jr , R Kirby Primm , Robert G Horn
PMCID: PMC429707  PMID: 984748

Abstract

Acute renal insufficiency developed in three patients receiving chemotherapy for tuberculosis. It is proposed that acute diffuse interstitial nephritis related to the drugs was responsible for the renal injury. Recovery of renal function was slow and incomplete. Physicians administering chemotherapy to patients with tuberculosis must be aware of the potential nephrotoxicity of the common treatment regimens.

Full text

PDF
167

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baldwin D. S., Levine B. B., McCluskey R. T., Gallo G. R. Renal failure and interstitial nephritis due to penicillin and methicillin. N Engl J Med. 1968 Dec 5;279(23):1245–1252. doi: 10.1056/NEJM196812052792302. [DOI] [PubMed] [Google Scholar]
  2. Chazan J. A., Garella S., Esparza A. Acute interstitial nephritis. A distinct clinico-pathological entity? Nephron. 1972;9(1):10–26. doi: 10.1159/000180130. [DOI] [PubMed] [Google Scholar]
  3. Churg J., Grishman E. Ultrastructure of immune deposits in renal glomeruli. Ann Intern Med. 1972 Mar;76(3):479–486. doi: 10.7326/0003-4819-76-3-479. [DOI] [PubMed] [Google Scholar]
  4. Cordonnier D., Muller J. M. Acute renal failure after rifampicin. Lancet. 1972 Dec 23;2(7791):1364–1365. doi: 10.1016/s0140-6736(72)92805-x. [DOI] [PubMed] [Google Scholar]
  5. Goldman A. L., Braman S. S. Isoniazid: a review with emphasis on adverse effects. Chest. 1972 Jul;62(1):71–77. doi: 10.1378/chest.62.1.71. [DOI] [PubMed] [Google Scholar]
  6. Kleinknecht D., Homberg J. C., Decroix G. Acute renal failure after rifampicin. Lancet. 1972 Jun 3;1(7762):1238–1239. doi: 10.1016/s0140-6736(72)90959-2. [DOI] [PubMed] [Google Scholar]
  7. Kovnat P., Labovitz E., Levison S. P. Antibiotics and the kidney. Med Clin North Am. 1973 Jul;57(4):1045–1063. doi: 10.1016/s0025-7125(16)32250-7. [DOI] [PubMed] [Google Scholar]
  8. Lyons H., Pinn V. W., Cortell S., Cohen J. J., Harrington J. T. Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome. N Engl J Med. 1973 Jan 18;288(3):124–128. doi: 10.1056/NEJM197301182880304. [DOI] [PubMed] [Google Scholar]
  9. Minetti L., di Belgiojoso G. B., Civati G., Durante A., Ratti F., Rovati C. Drug induced hypersensitivity nephritis. Proc Eur Dial Transplant Assoc. 1975;11:526–533. [PubMed] [Google Scholar]
  10. Simenhoff M. L., Guild W. R., Dammin G. J. Acute diffuse interstitial nephritis. Review of the literature and case report. Am J Med. 1968 Apr;44(4):618–625. doi: 10.1016/0002-9343(68)90063-6. [DOI] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES