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. 1976 Oct;10(4):765–767. doi: 10.1128/aac.10.4.765

Correlation of Resistance to Proflavine and Penicillin in Escherichia coli

Robin C McKellar 1, Colin N McKenzie 1, Donn J Kushner 1
PMCID: PMC429826  PMID: 791110

Abstract

A number of proflavine (PF)-resistant mutants of Escherichia coli B were also resistant to penicillin and cephalothin. Mutants resistant to 1.0 mM PF were 10 times more penicillin resistant than were the PF-susceptible, wild-type cells. Single-step mutants selected for resistance to either PF or penicillin were also resistant to the other drug. None of the resistant mutants tested possessed β-lactamase activity. These results suggest that resistance to PF and penicillin in E. coli B may be due to permeability changes in the cell envelope.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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