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. 1976 Nov;10(5):795–801. doi: 10.1128/aac.10.5.795

R Plasmids in Streptococcus agalactiae (Group B)

Thea Horodniceanu 1, D H Bouanchaud 1, G Bieth 1, Y A Chabbert 1
PMCID: PMC429839  PMID: 795369

Abstract

Two plasmids determining resistance to tetracycline (RIP500) and to chloramphenicol, erythromycin, lincomycin, and pristinamycin I (RIP501) were isolated from a strain of Streptococcus agalactiae. The frequency-of-resistance loss is very low for RIP500 (<3 × 104) but higher for RIP501 (the efficiency was dependent upon the curing agents and incubation temperature and varied between 0.5 and 96%). Derivatives susceptible to all drugs were also obtained. RIP500 and RIP501 have similar molecular weights (17.9 × 106 and 20 × 106, respectively) and represent different percentages of total deoxyribonucleic acid (0.4 and 4%, respectively). The number of copies of RIP500 and RIP501 per cell is different, and these plasmids are likely replicated under different kinds of control (stringent and/or relaxed). No plasmid deoxyribonucleic acid was found in a derivative of strain B96 susceptible to all drugs.

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Selected References

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