Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1977 Sep;12(3):346–348. doi: 10.1128/aac.12.3.346

Enhancement of Antistaphylococcal Activity of Nafcillin and Oxacillin by Sisomicin and Netilmicin

Chatrchai Watanakunakorn 1, Cheryl Glotzbecker 1
PMCID: PMC429916  PMID: 907328

Abstract

The in vitro activity of sisomicin, netilmicin, nafcillin, and oxacillin against 35 strains of Staphylococcus aureus isolated from blood cultures of patients with endocarditis or septicemia was studied. The effects of combinations of either of the two newer aminoglycosides and either of the two penicillinase-resistant penicillins on the killing of S. aureus were investigated. All S. aureus strains were susceptible to the four antibiotics. Enhancement of antistaphylococcal activity was demonstrated by the antibiotic combinations.

Full text

PDF
347

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Waitz J. A., Moss E. L., Jr, Drube C. G., Weinstein M. J. Comparative activity of sisomicin, gentamicin, kanamycin, and tobramycin. Antimicrob Agents Chemother. 1972 Dec;2(6):431–437. doi: 10.1128/aac.2.6.431. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Watanakunakorm C., Glotzbecker C. Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides. Antimicrob Agents Chemother. 1974 Dec;6(6):802–806. doi: 10.1128/aac.6.6.802. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Watanakunakorn C. Comparative in vitro activity of Sch 20656, netilmicin, gentamicin, and tobramycin. Antimicrob Agents Chemother. 1976 Aug;10(2):382–383. doi: 10.1128/aac.10.2.382. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES