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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1976 Apr;73(4):1237–1240. doi: 10.1073/pnas.73.4.1237

Dimethylsulfoxide-induced differentiation and hemoglobin synthesis in tissue cultures of rat erythroleukemia cells transformed by 7,12-dimethylbenz(a)anthracene.

N Kluge, W Ostertag, T Sugiyama, D Arndt-Jovin, G Steinheider, M Furusawa, S K Dube
PMCID: PMC430237  PMID: 817287

Abstract

Permanent cell lines from transplantable tumors from 7, 12-dimethylbenz(a)anthracene-induced erythroleukemia of the rat were established. These cell lines maintain their erythroid nature. Erythroid differentiation can be induced by dimethylsulfoxide. This is shown by decrease in cell size, appearance of red and benzidine positive cells, and induced synthesis of four out of six adult globin chains.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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