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. 1976 Jun;73(6):1877–1881. doi: 10.1073/pnas.73.6.1877

Protein-protein interaction in transport: periplasmic histidine-binding protein J interacts with P protein.

G F Ames, E N Spurich
PMCID: PMC430410  PMID: 778848

Abstract

A component of the high-affinity histidine transport system in Salmonella typhimurium, the periplasmic histidine-binding protein J, interacts with another transport component, the P protein. A mutant J protein, with a defective interaction site but intact histidine-binding site, can function in histidine transport if an appropriate compensating mutation is introduced in the P protein. The interaction between the J and P proteins is an obligatory step in transport. The significance of this interaction and of the involvement of the P protein in multiple transport functions is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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