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. 1976 Nov;73(11):4164–4168. doi: 10.1073/pnas.73.11.4164

Infinite allele model with varying mutation rate.

M Nei, R Chakraborty, P A Fuerst
PMCID: PMC431369  PMID: 1069306

Abstract

Available data suggest that the variation in mutation rate among protein loci follows the gamma distribution. Thus, taking into account this variation, formulae are developed for the distribution of allele frequencies, mean and variance of heterozygosity, expected number of alleles, proportion of polymorphic loci, and genetic distance. These formulae should be more appropriate for the analysis of gene frequency data for protein loci than equivalent formulae with constant mutation rate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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