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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1977 Aug;74(8):3533–3536. doi: 10.1073/pnas.74.8.3533

HLA-D associated alloantisera react with molecules similar to Ia antigens.

M J Giphart, J F Kaufman, A Fuks, D Albrechtsen, B G Solheim, J W Bruning, J L Strominger
PMCID: PMC431625  PMID: 302944

Abstract

Two human alloantisera specific to bone marrow-derived lymphocytes (B cells) were shown to precipitate polypeptide chains of 29,000 and 34,000 daltons from human lymphoblastoid B cell lines. These molecules are similar to murine Ia antigens and are also precipitated by a rabbit B-cell specific heteroantiserum. Since the alloantisera are thought to recognize determinants coded by HLA-D or closely linked loci, these data support the hypothesis that these B-cell specific alloantigens are the human counterpart of the mouse Ia antigens and may be the products of HLA-D.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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