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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1977 Nov;74(11):5131–5134. doi: 10.1073/pnas.74.11.5131

Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex.

J Silver, W A Russell, B L Reis, J A Frelinger
PMCID: PMC432114  PMID: 270749

Abstract

Alloantisera directed against the alloantigens determined by the I-E and I-C subregions of the murine major histocompatibility complex precipitate two components that have molecular weights of 35,000 and 29,000. These components, when analyzed by partial NH2-terminal sequencing, show no homology to two components of similar size determined by the I-A subregion. However, the large chain determined by the murine I-E and/or I-C subregion is homologous to the large chain of the human HLA-D region alloantigen, although the small chains isolated from these two species do not display any such homology.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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