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. 1975 Feb;72(2):586–589. doi: 10.1073/pnas.72.2.586

Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta.

R P Penttinen, J R Lichtenstein, G R Martin, V A McKusick
PMCID: PMC432358  PMID: 1054840

Abstract

Cells obtained from normal human skin synthesize predominantly type I collogen in culture. Cells obtained from the skin of an infant with a severe form of osteogenesis imperfecta were found to synthesize as much type III as type I collagen. Decreased synthesis of type I collagen could explain the tissue fragility observed in this case.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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