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. 1973 Mar;70(3):727–731. doi: 10.1073/pnas.70.3.727

An Attempt at an Integral Interpretation of Nerve Excitability

Eberhard Neumann *, David Nachmansohn †, Aharon Katchalsky ‡
PMCID: PMC433345  PMID: 4514985

Abstract

A qualitatively consistent integral interpretation of biochemical, electrophysiological, and biophysical data on nerve activity is given in terms of a basic excitation unit. This operational term models a dynamically coupled assembly of membrane components accounting for graded and all-or-none responses upon stimulation. The analysis contains a series of suggestions linking controversial interpretations and is aimed at stimulation of experimental studies providing the basis for a quantitative integral theory of nerve excitation.

Keywords: basic excitation unit, proteins and bioelectricity, acetylcholine receptor, threshold, synaptic transmission

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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