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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1973 Apr;70(4):1037–1040. doi: 10.1073/pnas.70.4.1037

Purification of Mouse Interferon by Affinity Chromatography on a Solid-Phase Immunoadsorbent

Jean D Sipe *, Jaqueline De Maeyer-Guignard , Bernard Fauconnier , Edward De Maeyer
PMCID: PMC433420  PMID: 4352220

Abstract

A solid-phase immunoadsorbent capable of binding mouse interferon has been prepared. Starting from crude tissue-culture material, interferon could be purified 1990 times in a single step of affinity chromatography. Overall recovery ranged from 55 to 103% with tissue culture and mouse-brain interferon; however, only 5% was obtained with Sendai virus-induced interferon from mouse serum.

Keywords: Newcastle disease virus

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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