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. 1973 Apr;70(4):1191–1194. doi: 10.1073/pnas.70.4.1191

Na+-Selective Ionophoric Material Derived from Electric Organ and Kidney Membranes

Adil E Shamoo 1,2,3, R Wayne Albers 1,2,3
PMCID: PMC433455  PMID: 4515616

Abstract

Material that increases black lipid-membrane (oxidized cholesterol) conductance has been demonstrated in the acid-soluble fraction of tryptic digests of membrane fractions from Electrophorus electric organ and beef kidney. The conductance change elicited by this material is highly selective for Na+. The activity of the material was greatly enhanced by passage through DEAE-cellulose. Activity could be destroyed by further incubation with Pronase. Since conductivity increases exponentially with dose of ionophore, the conductive unit may be an oligomer.

Keywords: Electrophorus, black lipid membranes, peptides

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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