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. 1973 May;70(5):1419–1422. doi: 10.1073/pnas.70.5.1419

Subunits of Human Chorionic Gonadotropin: Unbalanced Synthesis and Secretion by Clonal Cell Strains Derived from a Bronchogenic Carcinoma

Armen H Tashjian Jr *, Bruce D Weintraub †, Norma J Barowsky *, Alan S Rabson ‡, Saul W Rosen †
PMCID: PMC433510  PMID: 4514312

Abstract

Three clones of ectopic hormone-producing cells from a single human neoplasm (bronchogenic carcinoma) show different rates of synthesis and secretion of chorionic gonadotropin and its alpha and beta subunits. For each clone, the amount of one or the other subunit always exceeded that of the complete hormone molecule. These findings may be analogous to unbalanced immunoglobulin chain synthesis in certain forms of myeloma.

Keywords: ectopic hormones, cell culture, immunoassay

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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