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. 1973 May;70(5):1509–1513. doi: 10.1073/pnas.70.5.1509

Isolation, Structure, and Absolute Configuration of a New Natural Insect Juvenile Hormone from Manduca sexta

Kenneth J Judy 1,*, David A Schooley 1, Loren L Dunham 1, M S Hall 1, B John Bergot 1, John B Siddall 1
PMCID: PMC433531  PMID: 16592086

Abstract

Two juvenile hormones are isolated from organ cultures of corpora allata of the tobacco hornworm moth, Manduca sexta Johannson, and are purified by high-resolution liquid chromatography. These are identified as methyl (2E, 6E)-(10R)-10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate, a new natural hormone, and methyl (2E,6E) - (10R,11S) - 10,11 - epoxy - 3,7,11 - trimethyl-2,6-tridecadienoate. [14C]Methionine is incorporated only into their methoxycarbonyl group. Details of the in vitro techniques and the chemical proof of structures are presented. The significance of the occurrence of a new juvenile hormone and the new techniques used for production, isolation, and identification are discussed.

Keywords: organ culture, corpora allata, high-resolution liquid chromatography, tobacco hornworm

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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