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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1973 Aug;70(8):2313–2316. doi: 10.1073/pnas.70.8.2313

Self-association of Cholesterol in Aqueous Solution

Margaret E Haberland 1, Jacqueline A Reynolds 1
PMCID: PMC433725  PMID: 4525165

Abstract

Cholesterol has a maximum solubility in aqueous solutions of 1.8 μg/ml or 4.7 μM. It undergoes a thermodynamically reversible self-association with a critical micelle concentration of 25 to 40 nM at 25°. The cholesterol micelle is heterogeneous in size, probably rodlike in shape, and stabilized by an unusually high interaction energy between the aggregated monomers.

Keywords: micelles, critical micelle concentration

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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