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. 1960 Jun;39(6):904–908. doi: 10.1172/JCI104110

FURTHER EVIDENCE OF A RELATIVE LACK OF C-21 HYDROXYLATION IN CONGENITAL ADRENAL HYPERPLASIA *

Andrew G Frantz 1,2,3,†, Donald A Holub 1,2,3, Joseph W Jailer 1,2,3
PMCID: PMC441836  PMID: 13824597

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BONGIOVANNI A. M. Adrenogenital syndrome: uncomplicated and hypertensive forms. Pediatrics. 1958 Apr;21(4):661–667. [PubMed] [Google Scholar]
  2. BONGIOVANNI A. M., EBERLEIN W. R., CARA J. Studies on the metabolism of adrenal steroids in the adrenogenital syndrome. J Clin Endocrinol Metab. 1954 Apr;14(4):409–422. doi: 10.1210/jcem-14-4-409. [DOI] [PubMed] [Google Scholar]
  3. BONGIOVANNI A. M., EBERLEIN W. R. Plasma and urinary corticosteroids in the hypertensive form of congenital adrenal hyperplasia. J Biol Chem. 1956 Nov;223(1):85–94. [PubMed] [Google Scholar]
  4. BONGIOVANNI A. M. In vitro hydroxylation of steroids by whole adrenal homogenates of beef, normal man, and patients with the adrenogenital syndrome. J Clin Invest. 1958 Oct;37(10):1342–1347. doi: 10.1172/JCI103723. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BULASCHENKO H., DOHAN F. C., RICHARDSON E. M., TOUCHSTONE J. C. The excretion of pregnane-3alpha, 17alpha, 21-triol-20-one (tetrahydro S) in normal and pathologic urine. J Clin Endocrinol Metab. 1957 Feb;17(2):250–255. doi: 10.1210/jcem-17-2-250. [DOI] [PubMed] [Google Scholar]
  6. BUSH I. E. Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. Biochem J. 1952 Jan;50(3):370–378. doi: 10.1042/bj0500370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. BUSH I. E., WILLOUGHBY M. The excretion of allo tetrahydrocortisol in human urine. Biochem J. 1957 Dec;67(4):689–700. doi: 10.1042/bj0670689. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. CHRISTY N. P., WALLACE E. Z., JAILER J. W. The effect of intravenously-administered ACTH on plasma 17,21-dihydroxy-20-ketosteroids in normal individuals and in patients with disorders of the adrenal cortex. J Clin Invest. 1955 Jun;34(6):899–906. doi: 10.1172/JCI103146. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. COPE C. L. Steroid metabolism in a case of congenital adrenal hyperplasia. Br Med J. 1959 Mar 28;1(5125):815–817. doi: 10.1136/bmj.1.5125.815. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FUKUSHIMA D. K., GALLAGER T. F. Absence of 21-dehydroxylation in congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1958 Jul;18(7):694–698. doi: 10.1210/jcem-18-7-694. [DOI] [PubMed] [Google Scholar]
  11. JAILER J. W., GOLD J. J., VANDE WIELE R., LIEBERMAN S. 17alpha-hydroxyprogesterone and 21-desoxyhydrocortisone; their metabolism and possible role in congenital adrenal virilism. J Clin Invest. 1955 Nov;34(11):1639–1646. doi: 10.1172/JCI103217. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. JENKINS J. S., MEAKIN J. W., NELSON D. H., THORN G. W. Inhibition of adrenal steroid 11-oxygenation in the dog. Science. 1958 Aug 29;128(3322):478–480. doi: 10.1126/science.128.3322.478-a. [DOI] [PubMed] [Google Scholar]
  13. JENKINS J. S., POTHIER L., REDDY W. J., NELSON D. H., THORN G. W. Clinical experience with selective inhibition of adrenal function. Br Med J. 1959 Feb 14;1(5119):398–401. doi: 10.1136/bmj.1.5119.398. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. KELLEY V. C., ELY R. S., RAILE R. B. Metabolic studies in patients with congenital adrenal hyperplasia; effects of cortisone therapy. J Clin Endocrinol Metab. 1952 May;12(9):1140–1162. doi: 10.1210/jcem-12-9-1140. [DOI] [PubMed] [Google Scholar]
  15. LIDDLE G. W., ISLAND D., LANCE E. M., HARRIS A. P. Alterations of adrenal steroid patterns in man resulting from treatment with a chemical inhibitor of 11 beta-hydroxylation. J Clin Endocrinol Metab. 1958 Aug;18(8):906–912. doi: 10.1210/jcem-18-8-906. [DOI] [PubMed] [Google Scholar]
  16. NORYMBERSKI J. K., STUBBS R. D., WEST H. F. Assessment of adrenocortical activity by assay of 17-ketogenic steroids in urine. Lancet. 1953 Jun 27;1(6774):1276–1281. doi: 10.1016/s0140-6736(53)92414-3. [DOI] [PubMed] [Google Scholar]
  17. ROMANOFF L. P., RODRIGUEZ R. M., SEELYE J. M., PARENT C., PINCUS G. The urinary excretion of tetrahydrocortisol, 3 alpha-allotetrahydrocortisol and tetrahydrocortisone in young and elderly men and women. J Clin Endocrinol Metab. 1958 Nov;18(11):1285–1295. doi: 10.1210/jcem-18-11-1285. [DOI] [PubMed] [Google Scholar]
  18. SILBER R. H., PORTER C. C. The determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma. J Biol Chem. 1954 Oct;210(2):923–932. [PubMed] [Google Scholar]

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