Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1960 Dec;39(12):1777–1790. doi: 10.1172/JCI104202

IDIOPATHIC HYPERLIPEMIA: METABOLIC STUDIES IN AN AFFECTED FAMILY*

Richard J Havel 1,†, Robert S Gordon Jr 1
PMCID: PMC441903  PMID: 13712364

Full text

PDF
1779

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAXTER J. H., GOODMAN H. C., HAVEL R. J. Serum lipid and lipoprotein alterations in nephrosis. J Clin Invest. 1960 Mar;39:455–465. doi: 10.1172/JCI104058. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BRAGDON J. H. Colorimetric determination of blood lipides. J Biol Chem. 1951 Jun;190(2):513–517. [PubMed] [Google Scholar]
  3. BRAGDON J. H., HAVEL R. J., BOYLE E. Human serum lipoproteins. I. Chemical composition of four fractions. J Lab Clin Med. 1956 Jul;48(1):36–42. [PubMed] [Google Scholar]
  4. BRAGDON J. H., HAVEL R. J. In vivo effect of anti-heparin agents on serum lipids and lepoproteins. Am J Physiol. 1954 Apr;177(1):128–133. doi: 10.1152/ajplegacy.1954.177.1.128. [DOI] [PubMed] [Google Scholar]
  5. BROWN R. K., BOYLE E., ANFINSEN C. B. The enzymatic transformation of lipoproteins. J Biol Chem. 1953 Sep;204(1):423–434. [PubMed] [Google Scholar]
  6. CARLSON L. A., OLHAGEN B. Studies on a case of essential hyperlipemia: blood lipids, with special reference to the composition and metabolism of the serum glycerides before, during and after the course of a viral hepatitis. J Clin Invest. 1959 May;38(5):854–862. doi: 10.1172/JCI103867. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. DAY A. J., PETERS J. A. Observations on clearing factor inhibitor elaborated by cortisone in rabbits. Aust J Exp Biol Med Sci. 1958 Apr;36(2):121–132. doi: 10.1038/icb.1958.15. [DOI] [PubMed] [Google Scholar]
  8. DAY A. J., PETERS J. A. The effect of uranium acetate on heparin induced lipemia clearing. Aust J Exp Biol Med Sci. 1958 Feb;36(1):39–48. doi: 10.1038/icb.1958.5. [DOI] [PubMed] [Google Scholar]
  9. FREDRICKSON D. S., HAVEL R. J. The metabolism of chylomicra. I. The removal of palmitic acid-1-C14 labeled chylomicra from dog plasma. J Clin Invest. 1956 Sep;35(9):1025–1032. doi: 10.1172/JCI103348. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FRENCH J. E., MORRIS B. The removal of 14C-labelled chylomicron fat from the circulation in rats. J Physiol. 1957 Sep 30;138(2):326–339. doi: 10.1113/jphysiol.1957.sp005854. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GASKINS A. L., SCOTT R. B., KESSLER A. D. Report of three cases of idiopathic familial hyperlipemia: use of ACTH and cortisone. Pediatrics. 1953 May;11(5):480–488. [PubMed] [Google Scholar]
  12. GOFMAN J. W., RUBIN L., McGINLEY J. P., JONES H. B. Hyperlipoproteinemia. Am J Med. 1954 Oct;17(4):514–520. doi: 10.1016/0002-9343(54)90126-6. [DOI] [PubMed] [Google Scholar]
  13. GORDON R. S., Jr, CHERKES A. Unesterified fatty acid in human blood plasma. J Clin Invest. 1956 Feb;35(2):206–212. doi: 10.1172/JCI103265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. GORDON R. S., Jr Unesterified fatty acid in human blood plasma. II. The transport function of unesterified fatty acid. J Clin Invest. 1957 Jun;36(6 Pt 1):810–815. doi: 10.1172/JCI103486. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. HARPER P. V., Jr, NEAL W. B., Jr, HLAVACEK G. R. Lipid synthesis and transport in the dog. Metabolism. 1953 Jan;2(1):69–80. [PubMed] [Google Scholar]
  16. HAVEL R. J., EDER H. A., BRAGDON J. H. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest. 1955 Sep;34(9):1345–1353. doi: 10.1172/JCI103182. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. HAVEL R. J. Early effects of fat ingestion on lipids and lipoproteins of serum in man. J Clin Invest. 1957 Jun;36(6 Pt 1):848–854. doi: 10.1172/JCI103491. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. HAVEL R. J. Transport and metabolism of chylomicra. Am J Clin Nutr. 1958 Nov-Dec;6(6):662–668. doi: 10.1093/ajcn/6.6.662. [DOI] [PubMed] [Google Scholar]
  19. HERZSTEIN J., WANG C. I., ALDERSBERG D. Effect of heparin on plasma lipid partition in man: studies in normal persons and in patients with coronary atherosclerosis, nephrosis and primary hyperlipemia. Ann Intern Med. 1954 Feb;40(2):290–305. doi: 10.7326/0003-4819-40-2-290. [DOI] [PubMed] [Google Scholar]
  20. JOYNER C. R., Jr Essential hyperlipemia. Ann Intern Med. 1953 Apr;38(4):759–777. doi: 10.7326/0003-4819-38-4-759. [DOI] [PubMed] [Google Scholar]
  21. KLATSKIN G., GORDON M. Relationship between relapsing pancreatitis and essential hyperlipemia. Am J Med. 1952 Jan;12(1):3–23. doi: 10.1016/0002-9343(52)90164-2. [DOI] [PubMed] [Google Scholar]
  22. KLEIN E., LEVER W. F., FEKETE L. L. Defective lipemia clearing response to heparin in idiopathic hyperlipemia. J Invest Dermatol. 1959 Sep;33:91–97. doi: 10.1038/jid.1959.129. [DOI] [PubMed] [Google Scholar]
  23. KLEIN E., LEVER W. F. Inhibition of lipemia clearing activity by serum of patients with hyperlipemia. Proc Soc Exp Biol Med. 1957 Jul;95(3):565–567. doi: 10.3181/00379727-95-23292. [DOI] [PubMed] [Google Scholar]
  24. KORN E. D. Clearing factor, a heparin-activated lipoprotein lipase. II. Substrate specificity and activation of coconut oil. J Biol Chem. 1955 Jul;215(1):15–26. [PubMed] [Google Scholar]
  25. LEVER W. F., KLEIN E. The inhibition of lipemia-clearing by hyperlipemic serum. J Invest Dermatol. 1957 Dec;29(6):465–469. doi: 10.1038/jid.1957.122. [DOI] [PubMed] [Google Scholar]
  26. LEVER W. F., SMITH P. A., HURLEY N. A. Idiopathic hyperlipemia and primary hypercholesteremic xanthomatosis. III. Effects of intravenously administered heparin on the plasma proteins and lipids. J Invest Dermatol. 1954 Jan;22(1):71-84; discussion, 84-7. doi: 10.1038/jid.1954.9. [DOI] [PubMed] [Google Scholar]
  27. ROBINSON D. S., HARRIS P. M. The production of lipolytic activity in the circulation of the hind limb in response to heparin. Q J Exp Physiol Cogn Med Sci. 1959 Jan;44(1):80–90. doi: 10.1113/expphysiol.1959.sp001378. [DOI] [PubMed] [Google Scholar]
  28. RODBELL M. N-terminal amino acid and lipid composition of lipoproteins from chyle and plasma. Science. 1958 Mar 28;127(3300):701–702. doi: 10.1126/science.127.3300.701. [DOI] [PubMed] [Google Scholar]
  29. SPERRY W. M., WEBB M. A revision of the Schoenheimer-Sperry method for cholesterol determination. J Biol Chem. 1950 Nov;187(1):97–106. [PubMed] [Google Scholar]
  30. Stewart C. P., Hendry E. B. The phospholipins of blood. Biochem J. 1935 Jul;29(7):1683–1689. doi: 10.1042/bj0291683. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. WATKIN D. M., FROEB H. G., HATCH F. T., GUTMAN A. B. Effects of diet in essential hypertension. II. Results with unmodified Kempner rice diet in 50 hospitalized patients. Am J Med. 1950 Oct;9(4):441–493. doi: 10.1016/0002-9343(50)90200-2. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES