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. 1964 Nov;43(11):2132–2145. doi: 10.1172/JCI105087

The Effect of Prednisone on Calcium Metabolism and Ca47 Kinetics in Patients with Multiple Myeloma and Hypercalcemia *

Carl J Bentzel 1,2,3,†, Paul P Carbone 1,2,3, Leon Rosenberg 1,2,3, Millicent Bean 1,2,3
PMCID: PMC442001  PMID: 14223925

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADAMS W. S., MASON E. D., BASSETT S. H. Metabolic balance investigation of three cases of multiple myeloma during ACTH administration; exchanges of calcium, phosphorus, nitrogen and electrolytes. J Clin Invest. 1954 Feb;33(2):103–121. doi: 10.1172/JCI102877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ANDERSON J., HARPER C., DENT C. E., PHILPOT G. R. Effect of cortisone on calcium metabolism in sarcoidosis with hypercalcaemia; possibly antagonistic actions of cortisone and vitamin D. Lancet. 1954 Oct 9;267(6841):720–724. doi: 10.1016/s0140-6736(54)90492-4. [DOI] [PubMed] [Google Scholar]
  3. AUBERT J. P., BRONNER F., RICHELLE L. J. Quantitation of calcium metabolism. Theory. J Clin Invest. 1963 Jun;42:885–897. doi: 10.1172/JCI104781. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. AUBERT J. P., MILHAUD G. [Method for the measurement of the principal routes of calcium metabolism in man]. Biochim Biophys Acta. 1960 Mar 25;39:122–139. doi: 10.1016/0006-3002(60)90128-1. [DOI] [PubMed] [Google Scholar]
  5. BELL N. H., GILL J. R., Jr, BARTTER F. C. ON THE ABNORMAL CALCIUM ABSORPTION IN SARCOIDOSIS. EVIDENCE FOR INCREASED SENSITIVITY TO VITAMIN D. Am J Med. 1964 Apr;36:500–513. doi: 10.1016/0002-9343(64)90099-3. [DOI] [PubMed] [Google Scholar]
  6. BLAU M., SPENCER H., SWERNOV J., LASZLO D. Utilization and intestinal excretion of calcium in man. Science. 1954 Dec 17;120(3129):1029–1031. doi: 10.1126/science.120.3129.1029. [DOI] [PubMed] [Google Scholar]
  7. CLARK I., GEOFFROY F., BOWERS W. Effects of adrenal cortical steroids on calcium metabolism. Endocrinology. 1959 Jun;64(6):849–856. doi: 10.1210/endo-64-6-849. [DOI] [PubMed] [Google Scholar]
  8. COHN S. H., LIPPINCOTT S. W., GUSMANO E. A., ROBERTSON J. S. Comparative kinetics of Ca47 and Sr85 in man. Radiat Res. 1963 May;19:104–119. [PubMed] [Google Scholar]
  9. COLLINS E. J., GARRET E. R., JOHNSTON R. L. Effect of adrenal steroids on radio-calcium metabolism in dogs. Metabolism. 1962 Jul;11:716–726. [PubMed] [Google Scholar]
  10. GARRETT E. R., JOHNSTON R. L., COLLINS E. J. Kinetics of steroid effects on Ca-47 dynamics in dogs with the analog computer. II. J Pharm Sci. 1963 Jul;52:668–678. doi: 10.1002/jps.2600520715. [DOI] [PubMed] [Google Scholar]
  11. GLUECK H. I., WAYNE L., GOLDSMITH R. Abnormal calcium binding associated with hyperglobulinemia, clotting defects, and osteoporosis: a study of this relationship. J Lab Clin Med. 1962 Jan;59:40–64. [PubMed] [Google Scholar]
  12. GROLLMAN A. Effect of cortisone on serum calcium, magnesium and phosphate levels in nephrectomized dogs. Proc Soc Exp Biol Med. 1954 Apr;85(4):582–583. doi: 10.3181/00379727-85-20958. [DOI] [PubMed] [Google Scholar]
  13. HEANEY R. P., WHEDON G. D. Radiocalcium studies of bone formation rate in human metabolic bone disease. J Clin Endocrinol Metab. 1958 Nov;18(11):1246–1267. doi: 10.1210/jcem-18-11-1246. [DOI] [PubMed] [Google Scholar]
  14. HOWARD J. E., THOMAS W. C., Jr Clinical disorders of calcium homeostasis. Medicine (Baltimore) 1963 Jan;42:25–45. doi: 10.1097/00005792-196301000-00002. [DOI] [PubMed] [Google Scholar]
  15. Heaney R. P. Evaluation and interpretation of calcium-kinetic data in man. Clin Orthop Relat Res. 1963;31:153–183. [PubMed] [Google Scholar]
  16. King E. J., Armstrong A. R. A CONVENIENT METHOD FOR DETERMINING SERUM AND BILE PHOSPHATASE ACTIVITY. Can Med Assoc J. 1934 Oct;31(4):376–381. [PMC free article] [PubMed] [Google Scholar]
  17. LAAKE H. The action of corticosteroids on the renal reabsorption of calcium. Acta Endocrinol (Copenh) 1960 May;34:60–64. doi: 10.1530/acta.0.xxxiv0060. [DOI] [PubMed] [Google Scholar]
  18. LAZOR M. Z., ROSENBERG L. E. MECHANISM OF ADRENAL-STEROID REVERSAL OF HYPERCALCEMIA IN MULTIPLE MYELOMA. N Engl J Med. 1964 Apr 9;270:749–755. doi: 10.1056/NEJM196404092701501. [DOI] [PubMed] [Google Scholar]
  19. LAZOR M. Z., ROSENBERG L., CARBONE P. STUDIES OF CALCIUM METABOLISM IN MULTIPLE MYELOMA WITH CALCIUM AND METABOLIC-BALANCE TECHNIQUES. J Clin Invest. 1963 Aug;42:1238–1247. doi: 10.1172/JCI104809. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. MACINTYRE I. The flame-spectrophotometric determination of calcium in biological fluids and an isotopic analysis of the errors in the Kramer-Tisdall procedure. Biochem J. 1957 Sep;67(1):164–172. doi: 10.1042/bj0670164. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. MASS R. E. A comparison of the effect of prednisone and a placebo in the treatment of multiple myeloma. Cancer Chemother Rep. 1962 Feb;16:257–259. [PubMed] [Google Scholar]
  22. MORGAN H. G., MITCHELL R. G., STOWERS J. M., THOMSON J. Metabolic studies on two infants with idiopathic hypercalcaemia. Lancet. 1956 Jun 16;270(6929):925–931. doi: 10.1016/s0140-6736(56)91518-5. [DOI] [PubMed] [Google Scholar]
  23. PROCKOP D. J., UDENFRIEND S. A specific method for the analysis of hydroxyproline in tissues and urine. Anal Biochem. 1960 Nov;1:228–239. doi: 10.1016/0003-2697(60)90050-6. [DOI] [PubMed] [Google Scholar]
  24. SISSONS H. A. The osteoporosis of Cushing's syndrome. J Bone Joint Surg Br. 1956 Feb;38-B(1):418–433. doi: 10.1302/0301-620X.38B1.418. [DOI] [PubMed] [Google Scholar]
  25. SKOOG W. A., ADAMS W. S., MACDONALD N. S. Metabolic balance and Sr85 study of a patient with multiple myeloma treated with corticosteroids and androgens. Metabolism. 1962 Apr;11:421–434. [PubMed] [Google Scholar]
  26. SKOOG W. A., ADAMS W. S. Metabolic balance study of a patient with multiple myeloma treated with dexamethasone. Dexamethasone-induced fatal necrotizing polyarteritis of coronary vessels and kidneys. Am J Med. 1963 Mar;34:417–425. doi: 10.1016/0002-9343(63)90128-1. [DOI] [PubMed] [Google Scholar]
  27. TAUSSKY H. H., SHORR E. A microcolorimetric method for the determination of inorganic phosphorus. J Biol Chem. 1953 Jun;202(2):675–685. [PubMed] [Google Scholar]
  28. TORIBARA T. Y., TEREPKA A. R., DEWEY P. A. The ultrafiltrable calcium of human serum. I. Ultrafiltration methods and normal values. J Clin Invest. 1957 May;36(5):738–748. doi: 10.1172/JCI103477. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. WALSER M. The separate effects of hyperparathyroidism, hypercalcemia of malignancy, renal failure, and acidosis on the state of calcium, phosphate, and other ions in plasma. J Clin Invest. 1962 Jul;41:1454–1471. doi: 10.1172/JCI104601. [DOI] [PMC free article] [PubMed] [Google Scholar]

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