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. 1973 Mar;3(3):335–337. doi: 10.1128/aac.3.3.335

In Vitro Susceptibility of Neisseria gonorrhoeae to Spectinomycin Examined by a Broth Dilution Method

J Levy a,1, K Wicher a, N R Rose a
PMCID: PMC444411  PMID: 4275225

Abstract

The in vitro susceptibility of 113 strains of Neisseria gonorrhoeae to spectinomycin was determined by the broth dilution method and was compared with their susceptibility to penicillin and ampicillin. All strains demonstrated a susceptibility to spectinomycin in a range between 2.5 and 20 μg/ml; 96% of these strains were susceptible in a range from 5 to 10 μg/ml. The same strains were susceptible to ampicillin at concentrations between 0.06 and 0.5 μg/ml and to penicillin between 0.02 and 1.25 units/ml. For the majority of strains, the minimal inhibitory and bactercidal concentrations were identical; however, with more than 10% of the strains, the minimal inhibitory concentration was lower than the minimal bactericidal concentration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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