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. 1993 Mar 1;90(5):1736–1740. doi: 10.1073/pnas.90.5.1736

Successful transient introduction of Leishmania RNA virus into a virally infected and an uninfected strain of Leishmania.

T C Armstrong 1, M C Keenan 1, G Widmer 1, J L Patterson 1
PMCID: PMC45954  PMID: 8446586

Abstract

Viruses of Leishmania have recently been identified and characterized. These viruses are consistently double-stranded RNA viruses of approximately 5 kb. To date, they have not been reported to exist outside their protozoan host, nor have they been shown to be infectious. We report here the ability to transiently transfer these viruses to two strains of Leishmania, one previously infected and one that did not previously carry a virus. A PCR-based assay was used to detect viral negative-stranded RNA. Input RNA was ruled out as the source of template because a replication-incompetent (UV inactivated) virus was not detectable after transfer into Leishmania.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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