Abstract
In six normal subjects treatment with 4 mg nedocromil sodium failed to alter the cough and bronchoconstriction induced by inhaled capsaicin. Because nedocromil has previously been shown to inhibit reflex bronchoconstriction provoked by inhaled sulphur dioxide and inhaled bradykinin, the results suggest that inhaled capsaicin acts on different nerve fibres.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Allistone A., Collier J. G., Davidson R. N., Fuller R. W., Richardson P. S. The effect of intravenous sodium cromoglycate on the bronchoconstriction induced by sulphur dioxide inhalation in man. Clin Sci (Lond) 1985 Feb;68(2):227–232. doi: 10.1042/cs0680227. [DOI] [PubMed] [Google Scholar]
- Auty R. M. The clinical development of a new agent for the treatment of airway inflammation, nedocromil sodium (Tilade). Eur J Respir Dis Suppl. 1986;147:120–131. [PubMed] [Google Scholar]
- Dixon C. M., Fuller R. W., Barnes P. J. Effect of nedocromil sodium on sulphur dioxide induced bronchoconstriction. Thorax. 1987 Jun;42(6):462–465. doi: 10.1136/thx.42.6.462. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fuller R. W., Dixon C. M., Barnes P. J. Bronchoconstrictor response to inhaled capsaicin in humans. J Appl Physiol (1985) 1985 Apr;58(4):1080–1084. doi: 10.1152/jappl.1985.58.4.1080. [DOI] [PubMed] [Google Scholar]
- Fuller R. W., Dixon C. M., Cuss F. M., Barnes P. J. Bradykinin-induced bronchoconstriction in humans. Mode of action. Am Rev Respir Dis. 1987 Jan;135(1):176–180. doi: 10.1164/arrd.1987.135.1.176. [DOI] [PubMed] [Google Scholar]
- Lándsér F. J., Nagles J., Demedts M., Billiet L., van de Woestijne K. P. A new method to determine frequency characteristics of the respiratory system. J Appl Physiol. 1976 Jul;41(1):101–106. doi: 10.1152/jappl.1976.41.1.101. [DOI] [PubMed] [Google Scholar]