Skip to main content
Thorax logoLink to Thorax
. 1990 Jun;45(6):425–430. doi: 10.1136/thx.45.6.425

Physiology and treatment of cough.

R W Fuller 1, D M Jackson 1
PMCID: PMC462522  PMID: 2203180

Full text

PDF
427

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adcock J. J., Schneider C., Smith T. W. Effects of codeine, morphine and a novel opioid pentapeptide BW443C, on cough, nociception and ventilation in the unanaesthetized guinea-pig. Br J Pharmacol. 1988 Jan;93(1):93–100. doi: 10.1111/j.1476-5381.1988.tb11409.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Boushey H. A., Richardson P. S., Widdicombe J. G., Wise J. C. The response of laryngeal afferent fibres to mechanical and chemical stimuli. J Physiol. 1974 Jul;240(1):153–175. doi: 10.1113/jphysiol.1974.sp010605. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Choudry N. B., Fuller R. W., Pride N. B. Sensitivity of the human cough reflex: effect of inflammatory mediators prostaglandin E2, bradykinin, and histamine. Am Rev Respir Dis. 1989 Jul;140(1):137–141. doi: 10.1164/ajrccm/140.1.137. [DOI] [PubMed] [Google Scholar]
  4. Coleridge H. M., Coleridge J. C., Baker D. G., Ginzel K. H., Morrison M. A. Comparison of the effects of histamine and prostaglandin on afferent C-fiber endings and irritant receptors in the intrapulmonary airways. Adv Exp Med Biol. 1978;99:291–305. doi: 10.1007/978-1-4613-4009-6_32. [DOI] [PubMed] [Google Scholar]
  5. Collier J. G., Fuller R. W. Capsaicin inhalation in man and the effects of sodium cromoglycate. Br J Pharmacol. 1984 Jan;81(1):113–117. doi: 10.1111/j.1476-5381.1984.tb10750.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Corrao W. M., Braman S. S., Irwin R. S. Chronic cough as the sole presenting manifestation of bronchial asthma. N Engl J Med. 1979 Mar 22;300(12):633–637. doi: 10.1056/NEJM197903223001201. [DOI] [PubMed] [Google Scholar]
  7. Costello J. F., Dunlop L. S., Gardiner P. J. Characteristics of prostaglandin induced cough in man. Br J Clin Pharmacol. 1985 Oct;20(4):355–359. doi: 10.1111/j.1365-2125.1985.tb05077.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Cross B. A., Guz A., Jain S. K., Archer S., Stevens J., Reynolds F. The effect of anaesthesia of the airway in dog and man: a study of respiratory reflexes, sensations and lung mechanics. Clin Sci Mol Med. 1976 Jun;50(6):439–454. doi: 10.1042/cs0500439. [DOI] [PubMed] [Google Scholar]
  9. Cullen K. J., Stenhouse N. S., Welborn T. A., McCall M. G., Curnow D. H. Chronic respiratory disease in a rural community. Lancet. 1968 Sep 21;2(7569):657–660. doi: 10.1016/s0140-6736(68)92507-5. [DOI] [PubMed] [Google Scholar]
  10. Davies A., Dixon M., Callanan D., Huszczuk A., Widdicombe J. G., Wise J. C. Lung reflexes in rabbits during pulmonary stretch receptor block by sulphur dioxide. Respir Physiol. 1978 Jul;34(1):83–101. doi: 10.1016/0034-5687(78)90050-6. [DOI] [PubMed] [Google Scholar]
  11. Dixon M., Jackson D. M., Richards I. M. The effect of a respiratory tract infection on histamine-induced changes in lung mechanics and irritant receptor discharge in dogs. Am Rev Respir Dis. 1979 Oct;120(4):843–848. doi: 10.1164/arrd.1979.120.4.843. [DOI] [PubMed] [Google Scholar]
  12. ECKENHOFF J. E., COMROE J. H., Jr Blocking of tetraethylammonium on lobelin-induced thoracic pain. Proc Soc Exp Biol Med. 1951 Apr;76(4):725–726. doi: 10.3181/00379727-76-18608. [DOI] [PubMed] [Google Scholar]
  13. Eddy N. B., Friebel H., Hahn K. J., Halbach H. Codeine and its alternates for pain and cough relief . 4. Potential alternates for cough relief. Bull World Health Organ. 1969;40(5):639–719. [PMC free article] [PubMed] [Google Scholar]
  14. Eddy N. B., Friebel H., Hahn K. J., Halbach H. Codeine and its alternates for pain and cough relief. 3. The antitussive action of codeine--mechanism, methodology and evaluation. Bull World Health Organ. 1969;40(3):425–454. [PMC free article] [PubMed] [Google Scholar]
  15. Ellul-Micallef R. Effect of terbutaline sulphate in chronic "allergic" cough. Br Med J (Clin Res Ed) 1983 Oct 1;287(6397):940–943. doi: 10.1136/bmj.287.6397.940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Empey D. W., Laitinen L. A., Jacobs L., Gold W. M., Nadel J. A. Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am Rev Respir Dis. 1976 Feb;113(2):131–139. doi: 10.1164/arrd.1976.113.2.131. [DOI] [PubMed] [Google Scholar]
  17. Evald T., Munch E. P., Kok-Jensen A. Chronic non-asthmatic cough is not affected by inhaled beclomethasone dipropionate. A controlled double blind clinical trial. Allergy. 1989 Sep;44(7):510–514. doi: 10.1111/j.1398-9995.1989.tb04190.x. [DOI] [PubMed] [Google Scholar]
  18. Fuller R. W., Choudry N. B. Increased cough reflex associated with angiotensin converting enzyme inhibitor cough. Br Med J (Clin Res Ed) 1987 Oct 24;295(6605):1025–1026. doi: 10.1136/bmj.295.6605.1025-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Fuller R. W., Karlsson J. A., Choudry N. B., Pride N. B. Effect of inhaled and systemic opiates on responses to inhaled capsaicin in humans. J Appl Physiol (1985) 1988 Sep;65(3):1125–1130. doi: 10.1152/jappl.1988.65.3.1125. [DOI] [PubMed] [Google Scholar]
  20. Gulsvik A. Results of questionnaires and spirometry among non-smokers in Oslo. Eur J Respir Dis Suppl. 1982;118:15–25. [PubMed] [Google Scholar]
  21. Hansson L., Choudry N. B., Fuller R. W., Pride N. B. Effect of nedocromil sodium on the airway response to inhaled capsaicin in normal subjects. Thorax. 1988 Nov;43(11):935–936. doi: 10.1136/thx.43.11.935. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Higenbottam T. Cough induced by changes of ionic composition of airway surface liquid. Bull Eur Physiopathol Respir. 1984 Nov-Dec;20(6):553–562. [PubMed] [Google Scholar]
  23. Huber R., Deisenhofer J., Colman P. M., Matsushima M., Palm W. Crystallographic structure studies of an IgG molecule and an Fc fragment. Nature. 1976 Dec 2;264(5585):415–420. doi: 10.1038/264415a0. [DOI] [PubMed] [Google Scholar]
  24. Irwin R. S., Corrao W. M., Pratter M. R. Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of specific therapy. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):413–417. doi: 10.1164/arrd.1981.123.4.413. [DOI] [PubMed] [Google Scholar]
  25. Jammes Y., Fornaris E., Mei N., Barrat E. Afferent and efferent components of the bronchial vagal branches in cats. J Auton Nerv Syst. 1982 Mar;5(2):165–176. doi: 10.1016/0165-1838(82)90037-6. [DOI] [PubMed] [Google Scholar]
  26. Jeffery P., Reid L. Intra-epithelial nerves in normal rat airways: a quantitative electron microscopic study. J Anat. 1973 Jan;114(Pt 1):35–45. [PMC free article] [PubMed] [Google Scholar]
  27. KLASSEN K. P., MORTON D. R., CURTIS G. M. The clinical physiology of the human bronchi. III. The effect of vagus section on the cough reflex, bronchial caliber, and clearance of bronchial secretions. Surgery. 1951 Apr;29(4):483–490. [PubMed] [Google Scholar]
  28. Karczewski W., Widdicombe J. G. The effect of vagotomy, vagal cooling and efferent vagal stimulation on breathing and lung mechanics of rabbits. J Physiol. 1969 Apr;201(2):259–270. doi: 10.1113/jphysiol.1969.sp008754. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Karlsson J. A. Airway anaesthesia and the cough reflex. Bull Eur Physiopathol Respir. 1987;23 (Suppl 10):29s–36s. [PubMed] [Google Scholar]
  30. Karlsson J. A., Sant'Ambrogio G., Widdicombe J. Afferent neural pathways in cough and reflex bronchoconstriction. J Appl Physiol (1985) 1988 Sep;65(3):1007–1023. doi: 10.1152/jappl.1988.65.3.1007. [DOI] [PubMed] [Google Scholar]
  31. Kuhn J. J., Hendley J. O., Adams K. F., Clark J. W., Gwaltney J. M., Jr Antitussive effect of guaifenesin in young adults with natural colds. Objective and subjective assessment. Chest. 1982 Dec;82(6):713–718. doi: 10.1378/chest.82.6.713. [DOI] [PubMed] [Google Scholar]
  32. Kuhn J. J., Hendley J. O., Adams K. F., Clark J. W., Gwaltney J. M., Jr Antitussive effect of guaifenesin in young adults with natural colds. Objective and subjective assessment. Chest. 1982 Dec;82(6):713–718. doi: 10.1378/chest.82.6.713. [DOI] [PubMed] [Google Scholar]
  33. Leitch A. G., Lumb E. M., Kay A. B. Disodium cromoglycate relieves symptoms in symptomatic young smokers. A double blind placebo controlled trial. Allergy. 1984 Apr;39(3):211–215. doi: 10.1111/j.1398-9995.1984.tb02626.x. [DOI] [PubMed] [Google Scholar]
  34. McEwan J. R., Choudry N., Street R., Fuller R. W. Change in cough reflex after treatment with enalapril and ramipril. BMJ. 1989 Jul 1;299(6690):13–16. doi: 10.1136/bmj.299.6690.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. NADEL J. A., WIDDICOMBE J. G. Reflex effects of upper airway irritation on total lung resistance and blood pressure. J Appl Physiol. 1962 Nov;17:861–865. doi: 10.1152/jappl.1962.17.6.861. [DOI] [PubMed] [Google Scholar]
  36. Packman E. W., London S. J. The utility of artificially induced cough as a clinical model for evaluating the antitussive effects of aromatics delivered by inunction. Eur J Respir Dis Suppl. 1980;110:101–109. [PubMed] [Google Scholar]
  37. Paintal A. S. Vagal sensory receptors and their reflex effects. Physiol Rev. 1973 Jan;53(1):159–227. doi: 10.1152/physrev.1973.53.1.159. [DOI] [PubMed] [Google Scholar]
  38. Pattemore P. K., Asher M. I., Harrison A. C., Mitchell E. A., Rea H. H., Stewart A. W. Ethnic differences in prevalence of asthma symptoms and bronchial hyperresponsiveness in New Zealand schoolchildren. Thorax. 1989 Mar;44(3):168–176. doi: 10.1136/thx.44.3.168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Poe R. H., Israel R. H., Utell M. J., Hall W. J. Chronic cough: bronchoscopy or pulmonary function testing? Am Rev Respir Dis. 1982 Jul;126(1):160–162. doi: 10.1164/arrd.1982.126.1.160. [DOI] [PubMed] [Google Scholar]
  40. Pounsford J. C., Birch M. J., Saunders K. B. Effect of bronchodilators on the cough response to inhaled citric acid in normal and asthmatic subjects. Thorax. 1985 Sep;40(9):662–667. doi: 10.1136/thx.40.9.662. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Roberts A. M., Kaufman M. P., Baker D. G., Brown J. K., Coleridge H. M., Coleridge J. C. Reflex tracheal contraction induced by stimulation of bronchial C-fibers in dogs. J Appl Physiol Respir Environ Exerc Physiol. 1981 Aug;51(2):485–493. doi: 10.1152/jappl.1981.51.2.485. [DOI] [PubMed] [Google Scholar]
  42. Robinson N. P., Venning L., Kyle H., Widdicombe J. G. Quantitation of the secretory cells of the ferret tracheobronchial tree. J Anat. 1986 Apr;145:173–188. [PMC free article] [PubMed] [Google Scholar]
  43. Sant'Ambrogio G., Mathew O. P., Fisher J. T., Sant'Ambrogio F. B. Laryngeal receptors responding to transmural pressure, airflow and local muscle activity. Respir Physiol. 1983 Dec;54(3):317–330. doi: 10.1016/0034-5687(83)90075-0. [DOI] [PubMed] [Google Scholar]
  44. Sant'Ambrogio G., Mathew O. P., Sant'Ambrogio F. B., Fisher J. T. Laryngeal cold receptors. Respir Physiol. 1985 Jan;59(1):35–44. doi: 10.1016/0034-5687(85)90016-7. [DOI] [PubMed] [Google Scholar]
  45. Sears M. R., Jones D. T., Holdaway M. D., Hewitt C. J., Flannery E. M., Herbison G. P., Silva P. A. Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children. Thorax. 1986 Apr;41(4):283–289. doi: 10.1136/thx.41.4.283. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Simonsson B. G., Skoogh B. E., Bergh N. P., Andersson R., Svedmyr N. In vivo and in vitro effect of bradykinin on bronchial motor tone in normal subjects and patients with airways obstruction. Respiration. 1973;30(4):378–388. doi: 10.1159/000193051. [DOI] [PubMed] [Google Scholar]
  47. Tatar M., Webber S. E., Widdicombe J. G. Lung C-fibre receptor activation and defensive reflexes in anaesthetized cats. J Physiol. 1988 Aug;402:411–420. doi: 10.1113/jphysiol.1988.sp017212. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Vesco D., Kleisbauer J. P., Orehek J. Attenuation of bronchofiberscopy-induced cough by an inhaled beta 2-adrenergic agonist, fenoterol. Am Rev Respir Dis. 1988 Oct;138(4):805–806. doi: 10.1164/ajrccm/138.4.805. [DOI] [PubMed] [Google Scholar]
  49. WIDDICOMBE J. G. Respiratory reflexes from the trachea and bronchi of the cat. J Physiol. 1954 Jan;123(1):55–70. doi: 10.1113/jphysiol.1954.sp005033. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. WYNDER E. L., LEMON F. R., MANTEL N. EPIDEMIOLOGY OF PERSISTENT COUGH. Am Rev Respir Dis. 1965 May;91:679–700. doi: 10.1164/arrd.1965.91.5.679. [DOI] [PubMed] [Google Scholar]
  51. Woolcock A. J., Peat J. K., Salome C. M., Yan K., Anderson S. D., Schoeffel R. E., McCowage G., Killalea T. Prevalence of bronchial hyperresponsiveness and asthma in a rural adult population. Thorax. 1987 May;42(5):361–368. doi: 10.1136/thx.42.5.361. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES