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. 1993 Apr;48(4):404–405. doi: 10.1136/thx.48.4.404

Combined oesophageal adenocarcinoma and carcinoid in Barrett's oesophagitis: potential role of enterochromaffin-like cells in oesophageal malignancy.

N R Cary 1, D J Barron 1, J P McGoldrick 1, F C Wells 1
PMCID: PMC464444  PMID: 8511743

Abstract

A case of combined adenocarcinoma and carcinoid tumour which occurred in a patient with a Barrett's oesophagus is presented. Its significance is discussed in relation to the potential role of enterochromaffin-like cells in the development of oesophageal malignancy, and the possibility is raised that long term treatment with omeprazole, commonly used in this condition, could promote this.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ali M. H., Davidson A., Azzopardi J. G. Composite gastric carcinoid and adenocarcinoma. Histopathology. 1984 May;8(3):529–536. doi: 10.1111/j.1365-2559.1984.tb02362.x. [DOI] [PubMed] [Google Scholar]
  2. Brodman H. R., Pai B. N. Malignant carcinoid of the stomach and distal esophagus. Review of the literature and a case report. Am J Dig Dis. 1968 Jul;13(7):677–681. doi: 10.1007/BF02232978. [DOI] [PubMed] [Google Scholar]
  3. Chong F. K., Graham J. H., Madoff I. M. Mucin-producing carcinoid ("composite tumor") of upper third of esophagus: a variant of carcinoid tumor. Cancer. 1979 Nov;44(5):1853–1859. doi: 10.1002/1097-0142(197911)44:5<1853::aid-cncr2820440544>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
  4. Hawe A., Payne W. S., Weiland L. H., Fontana R. S. Adenocarcinima in the columnar epithelial lined lower (Barret) oesophagus. Thorax. 1973 Jul;28(4):511–514. doi: 10.1136/thx.28.4.511. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Larsson H., Carlsson E., Mattsson H., Lundell L., Sundler F., Sundell G., Wallmark B., Watanabe T., Håkanson R. Plasma gastrin and gastric enterochromaffinlike cell activation and proliferation. Studies with omeprazole and ranitidine in intact and antrectomized rats. Gastroenterology. 1986 Feb;90(2):391–399. doi: 10.1016/0016-5085(86)90938-8. [DOI] [PubMed] [Google Scholar]
  6. Rankin R., Nirodi N. S., Browne M. K. Carcinoid tumour of the oesophagus: report of a case. Scott Med J. 1980 Jul;25(3):245–249. doi: 10.1177/003693308002500313. [DOI] [PubMed] [Google Scholar]
  7. Thompson J. J., Zinsser K. R., Enterline H. T. Barrett's metaplasia and adenocarcinoma of the esophagus and gastroesophageal junction. Hum Pathol. 1983 Jan;14(1):42–61. doi: 10.1016/s0046-8177(83)80045-8. [DOI] [PubMed] [Google Scholar]

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