Skip to main content
PMC home page
Thorax logoLink to Thorax
. 1974 May;29(3):377–381. doi: 10.1136/thx.29.3.377

Brucella melitensis endocarditis: successful treatment of an infected prosthetic mitral valve

J B O'Meara 1, Susannah Eykyn 1, B S Jenkins 1, M V Braimbridge 1, I Phillips 1
PMCID: PMC470163  PMID: 4850832

Abstract

O'Meara, J. B., Eykyn, Susannah, Jenkins, B. S., Braimbridge, M. V., and Phillips, I. (1974).Thorax, 29, 377-381. Brucella melitensis endocarditis: successful treatment of an infected prosthetic mitral valve. A 38-year-old man had a mitral valve replacement for rheumatic calcific mitral stenosis and regurgitation; following this operation he remained well for 10 months. He then presented with cough, abdominal pain, and rigors, and Brucella melitensis type 3 was repeatedly isolated from blood cultures. His clinical condition deteriorated rapidly and an emergency valve replacement was performed. He was then treated with co-trimoxazole for 12 months and made an excellent recovery. This is the first reported case of brucella endocarditis arising de novo on a prosthetic heart valve.

Full text

PDF
377

Images in this article

378Image
on p.378

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CARIELLO M., TURSI L. ASPETTI EPIDEMIOLOGICI, CLINICI E MEDICO-SOCIALI DELLA BRUCELLOSI NEL MOLISE. Ann Sanita Pubblica. 1964 Sep-Oct;25:1041–1069. [PubMed] [Google Scholar]
  2. Fratini M., Milli G. C. Due casi di endocardite in corso di grave sepsi brucellare. G Mal Infett Parassit. 1968 Apr;20(4):373–377. [PubMed] [Google Scholar]
  3. GORLIN R., GORLIN S. G. Hydraulic formula for calculation of the area of the stenotic mitral valve, other cardiac valves, and central circulatory shunts. I. Am Heart J. 1951 Jan;41(1):1–29. doi: 10.1016/0002-8703(51)90002-6. [DOI] [PubMed] [Google Scholar]
  4. GRANT G. H., STOTE C. L. Rupture of the heart as a result of Br. abortus endocarditis. Br Med J. 1953 Apr 25;1(4816):914–916. doi: 10.1136/bmj.1.4816.914. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Galbraith N. S., Ross M. S., de Mowbray R. R., Payne D. J. Outbreak of Brucella melitensis type 2 infection in London. Br Med J. 1969 Mar 8;1(5644):612–614. doi: 10.1136/bmj.1.5644.612. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. HART F. D., MORGAN A., LACEY B. Brucella abortus endocarditis. Br Med J. 1951 May 12;1(4714):1048–1053. doi: 10.1136/bmj.1.4714.1048. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hassan A., Erian M. M., Farid Z., Hathout S. D., Sorensen K. Trimethoprim-sulphamethoxazole in acute brucellosis. Br Med J. 1971 Jul 17;3(5767):159–160. doi: 10.1136/bmj.3.5767.159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. JONES M. Subacute bacterial endocarditis of nonstreptococcic etiology; a review of the literature of the thirteen-year period 1936-1948 inclusive. Am Heart J. 1950 Jul;40(1):106–116. doi: 10.1016/0002-8703(50)90154-2. [DOI] [PubMed] [Google Scholar]
  9. Kaiser G. C., Willman V. L., Thurmann M., Hanlon C. R. Value replacement in cases of aortic insufficiency due to active endocarditis. J Thorac Cardiovasc Surg. 1967 Oct;54(4):491–502. [PubMed] [Google Scholar]
  10. Kerr W. R., McCaughey W. J., Coghlan J. D., Payne D. J., Quaife R. A., Robertson L., Farrell I. D. Techniques and interpretations in the serological diagnosis of brucellosis in man. J Med Microbiol. 1968 Nov;1(2):181–193. doi: 10.1099/00222615-1-2-181. [DOI] [PubMed] [Google Scholar]
  11. PEERY T. M., BELTER L. F. Brucellosis and heart disease. II. Fatal brucellosis: a review of the literature and report of new cases. Am J Pathol. 1960 Jun;36:673–697. [PMC free article] [PubMed] [Google Scholar]
  12. Phillips I., Eykyn S., Laker M. Outbreak of hospital infection caused by contaminated autoclaved fluids. Lancet. 1972 Jun 10;1(7763):1258–1260. doi: 10.1016/s0140-6736(72)90981-6. [DOI] [PubMed] [Google Scholar]
  13. Shafer R. B., Hall W. H. Bacterial endocarditis following open heart surgery. Am J Cardiol. 1970 May;25(5):602–607. doi: 10.1016/0002-9149(70)90599-0. [DOI] [PubMed] [Google Scholar]
  14. VOGLER W. R., DORNEY E. R., BRIDGES H. A. Bacterial endocarditis. A review of 148 cases. Am J Med. 1962 Jun;32:910–921. doi: 10.1016/0002-9343(62)90037-2. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES