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. 1980 Feb;35(2):140–144. doi: 10.1136/thx.35.2.140

Mycoplasma pneumonia with fulminant evolution into diffuse interstitial fibrosis.

J M Kaufman, C A Cuvelier, M Van der Straeten
PMCID: PMC471240  PMID: 7376118

Abstract

A fatal case of interstitial pneumonia caused by Mycoplasma pneumoniae with fulminant evolution into diffuse interstitial fibrosis is reported. Treatment with tetracycline and corticosteroids failed to arrest the progress of the disease. Fatal Mycoplasma pneumoniae infections have been reported previously and some degree of pulmonary fibrosis has been described in a few cases but as far as could be ascertained there are no other well-documented cases of diffuse interstitial fibrosis with proved Mycoplasma pneumoniae infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benisch B. M., Fayemi A., Gerber M. A., Axelrod J. Mycoplasmal pneumonia in a patient with rheumatic heart disease. Am J Clin Pathol. 1972 Sep;58(3):343–348. doi: 10.1093/ajcp/58.3.343. [DOI] [PubMed] [Google Scholar]
  2. Brolin I., Wernstedt L. Radiographic appearance of mycoplasmal pneumonai. Scand J Respir Dis. 1978 Aug;59(4):179–189. [PubMed] [Google Scholar]
  3. Chester A., Kane J., Garagusi V. Mycoplasma pneumonia with bilateral pleural effusions. Am Rev Respir Dis. 1975 Sep;112(3):451–456. doi: 10.1164/arrd.1975.112.3.451. [DOI] [PubMed] [Google Scholar]
  4. Crystal R. G., Fulmer J. D., Roberts W. C., Moss M. L., Line B. R., Reynolds H. Y. Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Ann Intern Med. 1976 Dec;85(6):769–788. doi: 10.7326/0003-4819-85-6-769. [DOI] [PubMed] [Google Scholar]
  5. De Vos M., Straeten M., Druyts E. Myocarditis and severe bilateral bronchopneumonia caused by Mycoplasma pneumoniae. Infection. 1976;4(1 Suppl):60–63. doi: 10.1007/BF01638427. [DOI] [PubMed] [Google Scholar]
  6. De Vos M., Van der Straeten M., Druyts E. Mycoplasma pneumoniae as a cause of pneumonia, lung abscess and pleural effusion: a case report. Infection. 1976;4(1 Suppl):58–59. doi: 10.1007/BF01638426. [DOI] [PubMed] [Google Scholar]
  7. Denny F. W., Clyde W. A., Jr, Glezen W. P. Mycoplasma pneumoniae disease: clinical spectrum, pathophysiology, epidemiology, and control. J Infect Dis. 1971 Jan;123(1):74–92. doi: 10.1093/infdis/123.1.74. [DOI] [PubMed] [Google Scholar]
  8. Foy H. M., Loop J., Clarke E. R., Mansy A. W., Spence W. F., Feigl P., Grayston J. T. Radiographic study of mycoplasma pneumoniae pneumonia. Am Rev Respir Dis. 1973 Sep;108(3):469–474. doi: 10.1164/arrd.1973.108.3.469. [DOI] [PubMed] [Google Scholar]
  9. Fraire A. E., Greenberg S. D., O'Neal R. M., Weg J. G., Jenkins D. E. Diffuse interstitial fibrosis of the lung. Am J Clin Pathol. 1973 May;59(5):636–647. doi: 10.1093/ajcp/59.5.636. [DOI] [PubMed] [Google Scholar]
  10. Gump D. W., Hawley H. B. Severe Mycoplasma pneumoniae pneumonia. Respiration. 1976;33(6):475–486. doi: 10.1159/000193765. [DOI] [PubMed] [Google Scholar]
  11. Hinson K. F. Diffuse pulmonary fibrosis. Hum Pathol. 1970 Jun;1(2):275–288. doi: 10.1016/s0046-8177(70)80040-5. [DOI] [PubMed] [Google Scholar]
  12. Holt S., Ryan W. F., Epstein E. J. Severe mycoplasma pneumonia. Thorax. 1977 Feb;32(1):112–115. doi: 10.1136/thx.32.1.112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Jones G. R., Borthwick R. C. Mycoplasma pneumonia resistant to oxytetracycline: two case reports. Br J Dis Chest. 1973 Apr;67(2):119–122. doi: 10.1016/0007-0971(73)90040-5. [DOI] [PubMed] [Google Scholar]
  14. Jones M. C. Mycoplasma pneumonia. Practitioner. 1969 Dec;203(218):751–759. [PubMed] [Google Scholar]
  15. Levine D. P., Lerner A. M. The clinical spectrum of Mycoplasma pneumoniae infections. Med Clin North Am. 1978 Sep;62(5):961–978. doi: 10.1016/s0025-7125(16)31749-7. [DOI] [PubMed] [Google Scholar]
  16. Luna M. A., Bedrossian C. W., Lichtiger B., Salem P. A. Interstitial pneumonitis associated with bleomycin therapy. Am J Clin Pathol. 1972 Nov;58(5):501–510. doi: 10.1093/ajcp/58.5.501. [DOI] [PubMed] [Google Scholar]
  17. Maisel J. C., Babbitt L. H., John T. J. Fatal Mycoplasma pneumoniae infection with isolation of organisms from lung. JAMA. 1967 Oct 23;202(4):287–290. [PubMed] [Google Scholar]
  18. Meyers B. R., Hirschman S. Z. Fatal infections associated with Mycoplasma pneumoniae: discussion of three cases with necropsy findings. Mt Sinai J Med. 1972 May-Jun;39(3):258–264. [PubMed] [Google Scholar]
  19. Murray H. W., Masur H., Senterfit L. B., Roberts R. B. The protean manifestations of Mycoplasma pneumoniae infection in adults. Am J Med. 1975 Feb;58(2):229–242. doi: 10.1016/0002-9343(75)90574-4. [DOI] [PubMed] [Google Scholar]
  20. Nastro J. A., Littner M. R., Tashkin D. P., Cassan S. M. Diffuse, pulmonary, interstitial infiltrate and mycoplasmal pneumonia. Am Rev Respir Dis. 1974 Nov;110(5):659–662. doi: 10.1164/arrd.1974.110.5.659. [DOI] [PubMed] [Google Scholar]
  21. Noriega E. R., Simberkoff M. S., Gilroy F. J., Rahal J. J., Jr Life-threatening Mycoplasma pneumoniae pneumonia. JAMA. 1974 Sep 9;229(11):1471–1472. [PubMed] [Google Scholar]
  22. POKORNY C., HELLWIG C. A. Diffuse interstitial fibrosis of the lungs. AMA Arch Pathol. 1955 Mar;59(3):382–387. [PubMed] [Google Scholar]
  23. Sands M. J., Jr, Satz J. E., Turner W. E., Jr, Soloff L. A. Pericarditis and perimyocarditis associated with active Mycoplasma pneumoniae infection. Ann Intern Med. 1977 May;86(5):544–548. doi: 10.7326/0003-4819-86-5-544. [DOI] [PubMed] [Google Scholar]
  24. Scadding J. G., Hinson K. F. Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs). Correlation of histology at biopsy with prognosis. Thorax. 1967 Jul;22(4):291–304. doi: 10.1136/thx.22.4.291. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Sevitt S. Diffuse and focal oxygen pneumonitis. A preliminary report on the threshold of pulmonary oxygen toxicity in man. J Clin Pathol. 1974 Jan;27(1):21–30. doi: 10.1136/jcp.27.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Simpson D. L., Goodman M., Spector S. L., Petty T. L. Long-term follow-up and bronchial reactivity testing in survivors of the adult respiratory distress syndrome. Am Rev Respir Dis. 1978 Mar;117(3):449–454. doi: 10.1164/arrd.1978.117.3.449. [DOI] [PubMed] [Google Scholar]
  27. Stokes D., Sigler A., Khouri N. F., Talamo R. C. Unilateral hyperlucent lung (Swyer-James syndrome) after severe Mycoplasma pneumoniae infection. Am Rev Respir Dis. 1978 Jan;117(1):145–152. doi: 10.1164/arrd.1978.117.1.145. [DOI] [PubMed] [Google Scholar]
  28. Weisenburger D. D. Interstitial pneumonitis associated with azathioprine therapy. Am J Clin Pathol. 1978 Feb;69(2):181–185. doi: 10.1093/ajcp/69.2.181. [DOI] [PubMed] [Google Scholar]
  29. Zinserling A. Pecularities of lesions in viral and mycoplasma infections of the respiratory tract. Virchows Arch A Pathol Pathol Anat. 1972;356(3):259–273. doi: 10.1007/BF00543159. [DOI] [PubMed] [Google Scholar]

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